Evidence map›Paper›PMID 26113765›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2015

Monte Carlo simulation of inverse geometry x-ray fluoroscopy using a modified MC-GPU framework.

David A P Dunkerley, Michael T Tomkowiak, Jordan M Slagowski, Bradley P McCabe, Tobias Funk, Michael A Speidel

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David A P DunkerleyDept. of Medical Physics, University of Wisconsin, Madison, WI, USA.
Michael T TomkowiakDept. of Medical Physics, University of Wisconsin, Madison, WI, USA.
Jordan M SlagowskiDept. of Medical Physics, University of Wisconsin, Madison, WI, USA.
Bradley P McCabeDept. of Radiation Oncology, University of Chicago, Chicago, IL, USA.
Tobias FunkTriple Ring Technologies, Inc, Newark, CA, USA.
Michael A SpeidelDept. of Medical Physics, University of Wisconsin, Madison, WI, USA.

Funding

Low-Dose Tomosynthetic Interventional System For Quantitative Cardiac ImagingR01HL084022 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SPEIDEL, MICHAEL A · 2007 to 2015
$4.4M
A low-dose fluoroscope for pediatric interventional cardiologyRC1HL100436 · NHLBI · TRIPLE RING TECHNOLOGIES, INC. · PI FUNK, TOBIAS · 2009 to 2010
$960k
NHLBI NIH HHS R01 HL084022NHLBI NIH HHS RC1 HL100436
6 · The paper itself

Abstract

Scanning-Beam Digital X-ray (SBDX) is a technology for low-dose fluoroscopy that employs inverse geometry x-ray beam scanning. To assist with rapid modeling of inverse geometry x-ray systems, we have developed a Monte Carlo (MC) simulation tool based on the MC-GPU framework. MC-GPU version 1.3 was modified to implement a 2D array of focal spot positions on a plane, with individually adjustable x-ray outputs, each producing a narrow x-ray beam directed toward a stationary photon-counting detector array. Geometric accuracy and blurring behavior in tomosynthesis reconstructions were evaluated from simulated images of a 3D arrangement of spheres. The artifact spread function from simulation agreed with experiment to within 1.6% (rRMSD). Detected x-ray scatter fraction was simulated for two SBDX detector geometries and compared to experiments. For the current SBDX prototype (10.6 cm wide by 5.3 cm tall detector), x-ray scatter fraction measured 2.8-6.4% (18.6-31.5 cm acrylic, 100 kV), versus 2.1-4.5% in MC simulation. Experimental trends in scatter versus detector size and phantom thickness were observed in simulation. For dose evaluation, an anthropomorphic phantom was imaged using regular and regional adaptive exposure (RAE) scanning. The reduction in kerma-area-product resulting from RAE scanning was 45% in radiochromic film measurements, versus 46% in simulation. The integral kerma calculated from TLD measurement points within the phantom was 57% lower when using RAE, versus 61% lower in simulation. This MC tool may be used to estimate tomographic blur, detected scatter, and dose distributions when developing inverse geometry x-ray systems.

Indexed as

inverse geometryMC-GPUMonte Carloscanning-beam digital x-rayX-ray fluoroscopy

Identifiers

PMID26113765
PMCPMC4476537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.