Evidence map›Paper›PMID 26113531›Full record

ArticleBlood2015

Ebf1 in DNA repair and leukemogenesis.

Katia Georgopoulos

Abstract readComment
In one paragraph

Article in Blood, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Katia GeorgopoulosHARVARD MEDICAL SCHOOL.

Funding

Role of IKAROS in the Biology and Therapy of High-Risk Precursor B-Cell LeukemiaR01CA190964 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GEORGOPOULOS, KATIA, VAN ETTEN, RICHARD A. · 2015 to 2019
$2.7M
Ikaros-based epigenetic regulation of T cell leukemogenesisR01CA158006 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI GEORGOPOULOS, KATIA · 2012 to 2016
$2.0M
Ikaros regulation: study on hemo-lymphopoiesisR01CA162092 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI GEORGOPOULOS, KATIA · 2011 to 2015
$1.8M
NCI NIH HHS R01 CA158006NCI NIH HHS R01 CA162092NCI NIH HHS R01 CA190964
6 · The paper itself

Abstract

In this issue of Blood, Prasad et al provide evidence for a new role for the B-lineage transcriptional regulator early B-cell factor 1 (Ebf1) during early B-cell development and B-cell acute lymphoblastic leukemia (B-ALL).

Indexed as

AnimalsCell Transformation, NeoplasticDNA DamagePAX5 Transcription FactorPrecursor Cells, B-LymphoidTrans-ActivatorsPAX5 Transcription FactorTrans-Activators

Identifiers

PMID26113531
PMCPMC4481587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.