Evidence map›Paper›PMID 26113125›Full record

ArticleHealth and quality of life outcomes2015

Impact of overactive bladder on quality of life and resource use: results from Korean Burden of Incontinence Study (KOBIS).

Kyu Sung Lee, Myung Soo Choo, Ju Tae Seo, Seung June Oh, Hyeong Gon Kim, Kwong Ng, Kyung Jin Lee, Jonathan T Tan, Joon Chul Kim

Open access · goldAbstract read
In one paragraph

Article in Health and quality of life outcomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  4. Observational
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  7. The impact of overactive bladder on health-related quality of life in Korea: based on the results of a Korean Community Health Survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Kyu Sung LeeSamsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-Gu, Seoul, South Korea. ksleedr@skku.edu.
Myung Soo ChooAsan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro, 43-Gil, Songpa-Gu, Seoul, South Korea. mschoo@amc.seoul.kr.
Ju Tae SeoCheil General Hospital, Dankoo University College of Medicine, 1-19 Mukjeong-Dong, Jung-Gu, Seoul, South Korea. jtandro@cgh.co.kr.
Seung June OhSeoul National University Hospital, 101 Daehak-Ro, Jongno-Gu, Seoul, South Korea. sjo@snu.ac.kr.
Hyeong Gon KimKonkuk University School of Medicine, Konkuk University Medical Center, Gwangjin-Gu, Seoul, South Korea. khgsjh@kuh.ac.kr.
Kwong NgAllergan APAC, Pasir Panjang Road, MBC, West Building #09-25, Singapore, 117439, Singapore. Ng_kwong@allergan.com.
Kyung Jin LeeAllergan Korea, GT Tower 14F, 1317-23, Seocho-dong, Seocho-gu, Seoul. Lee_Kate@allergan.com.
Jonathan T TanAllergan APAC, Pasir Panjang Road, MBC, West Building #09-25, Singapore, 117439, Singapore. Tan_jonathan@allergan.com.
Joon Chul KimBucheon St.Mary's Hospital, 2 Sosa-Dong, Wonmi-Gu, Gyeonggido, South Korea. kjc@catholic.ac.kr.
Allergan (South Korea) · KRKonkuk University Medical Center · KRSeoul National University Hospital · KRSungkyunkwan University · KRThe Catholic University of Korea Bucheon St. Mary's Hospital · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the impact of overactive bladder (OAB) on quality of life (QOL), resource use and productivity loss in patients recruited from six hospitals in Korea.

methodsThis cross-sectional survey recruited 625 OAB patients between July to December 2013. Patients were categorised into four groups based on the average number of urinary incontinence (UI) episodes over the past three days (0, 1, 2-3 and ≥4 UI/day). QOL was measured using the Incontinence-Specific Quality of Life Instrument (I-QOL), the Overactive Bladder Questionnaire (OAB-q), and a generic health-related utility instrument (EQ-5D). Information on hospital and clinic visit frequency, and continence pads use were also collected. Work productivity was assessed using the Work Productivity and Activity Impairment (WPAI) questionnaire. Between group differences were assessed using ANOVA. Multivariable regression analyses were performed to examine the independent effects of OAB symptoms on QOL.

resultsSeverity of UI showed a significant linear relationship with QOL, with clinically meaningful differences between each UI severity category. Compared to the dry category, patients in the most severe category (≥4 UI/day) had significantly lower I-QOL scores (69.8 vs 42.6; p < 0.0001), greater symptom bother on the OAB-q (30.4 vs 64.6; p < 0.0001), and poorer EQ-5D utility (0.848 vs 0.742; p < 0.001). Multivariable analyses showed that UI severity, frequency, urgency, and nocturia are independently associated with poorer QOL. Incontinence severity is also significantly associated with cost of incontinence pads (p < 0.0001), and a greater interference with work and regular activities (p = 0.001), however, no significant difference in hospital and clinic visits were observed.

conclusionSeverity of UI is a key contributor to the disease burden of OAB in Korean patients, even after taking into account the impact of other symptoms associated with OAB.

Indexed as

Adaptation, PsychologicalAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPatient Acceptance of Health CareQuality of LifeRepublic of KoreaSeverity of Illness IndexSurveys and QuestionnairesUrinary Bladder, OveractiveUrinary Incontinence

Identifiers

PMID26113125
PMCPMC4480453
OpenAlexW2171122134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.