Evidence map›Paper›PMID 26112989›Full record

ReviewDigestive diseases and sciences2015

Cirrhotic Multiorgan Syndrome.

Søren Møller, Flemming Bendtsen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Diagnosis of Portal Hypertension.Diagnostics (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. [Analysis of clinical characteristics and risk factors for nosocomial mortality in patients with liver cirrhosis combined with atrial arrhythmia].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
  7. Review
  8. Article
  9. [Advances in anticoagulant therapy for cirrhosis combined with atrial fibrillation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Cirrhotic Cardiomyopathy: A New Clinical Phenotype.Arquivos brasileiros de cardiologia · 2017
    Review
  18. Diastolic dysfunction in cirrhosis.Heart failure reviews · 2016
    Review
  19. Article
  20. Diagnosis and Management of Cirrhotic Cardiomyopathy.Journal of clinical and experimental hepatology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Søren MøllerCenter for Functional and Diagnostic Imaging and Research, Department of Clinical Physiology and Nuclear Medicine, Faculty of Health Sciences, Copenhagen University Hvidovre Hospital, Kettegaard alle 30, 2650, Hvidovre, Denmark. soeren.moeller@regionh.dk.
Flemming BendtsenGastro Unit, Medical Division, Faculty of Health Sciences, Copenhagen University Hvidovre Hospital, Kettegaard alle 30, 2650, Hvidovre, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cirrhosis and portal hypertension are at an increased risk of the development of circulatory dysfunction that may potentially result in multiple organ failure. Apart from the liver, this may involve the heart, lungs, kidneys, the immune system, the adrenal glands, and other organ systems. As the disease progresses, the circulation becomes hyperdynamic, and signs of cardiac, pulmonary, and renal dysfunction are observed, in addition to reduced survival. Infections and an altered cardiac function known as cirrhotic cardiomyopathy may be precipitators for the development of other complications such as hepatorenal syndrome. In patients with chronic organ dysfunction, various precipitating events may induce an acute-on-chronic renal failure and acute-on-chronic liver failure that negatively affect the prognosis. Future research on the pathophysiologic mechanisms of the complications and the precipitating factors is essential to understand the basics of the treatment of these challenging conditions. The aim of the present review is to focus on the development and precipitating factors of various organ failures in patients with decompensated cirrhosis.

Indexed as

Acute Kidney InjuryAcute-On-Chronic Liver FailureAnimalsCardiomyopathiesDisease ProgressionHemodynamicsHumansHypertension, PortalKidney Failure, ChronicLiver CirrhosisMultiple Organ FailurePrognosisRisk FactorsSyndromeCirrhosisCirrhotic cardiomyopathyHyperdynamic syndromePortal hypertensionPulmonary dysfunction

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.