ReviewCurrent psychiatry reports2015
Chronobiology of bipolar disorder: therapeutic implication.
Review in Current psychiatry reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
- Blue-blocking glasses as additive treatment for mania: a randomized placebo-controlled trial.Bipolar disorders · 2016Trial
- Article
- Role of adjunctive nonpharmacological strategies for treatment of rapid-cycling bipolar disorder.World journal of psychiatry · 2023Review
- Privacy-Preserving Federated Model Predicting Bipolar Transition in Patients With Depression: Prediction Model Development Study.Journal of medical Internet research · 2023Article
- Spectrophotometric properties of commercially available blue blockers across multiple lighting conditions.Chronobiology international · 2022Article
- Pharmacotherapeutic management of insomnia and effects on sleep processes, neural plasticity, and brain systems modulating stress: A narrative review.Frontiers in neuroscience · 2022Review
- Overcoming Compensatory Mechanisms toward Chronic Drug Administration to Ensure Long-Term, Sustainable Beneficial Effects.Molecular therapy. Methods & clinical development · 2020Review
- Sleep, insomnia, and depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
- Neuroinflammation in Bipolar Depression.Frontiers in psychiatry · 2020Review
- Investigating the relationship between melatonin levels, melatonin system, microbiota composition and bipolar disorder psychopathology across the different phases of the disease.International journal of bipolar disorders · 2019Article
- The human hypothalamus in mood disorders: The HPA axis in the center.IBRO reports · 2019Review
- Circadian Disruptions in the Myshkin Mouse Model of Mania Are Independent of Deficits in Suprachiasmatic Molecular Clock Function.Biological psychiatry · 2018Article
- Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice.The Journal of biological chemistry · 2018Article
- The association between mood state and chronobiological characteristics in bipolar I disorder: a naturalistic, variable cluster analysis-based study.International journal of bipolar disorders · 2018Article
- Genetic Factors Affecting Seasonality, Mood, and the Circadian Clock.Frontiers in endocrinology · 2018Review
- The Biological Rhythms Interview of Assessment in Neuropsychiatry in patients with bipolar disorder: correlation with affective temperaments and schizotypy.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2016Article
- Clinical significance of mobile health assessed sleep duration and variability in bipolar disorder.Journal of psychiatric research · 2016Article
- Circadian Clocks as Modulators of Metabolic Comorbidity in Psychiatric Disorders.Current psychiatry reports · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple lines of evidence suggest that psychopathological symptoms of bipolar disorder arise in part from a malfunction of the circadian system, linking the disease with an abnormal internal timing. Alterations in circadian rhythms and sleep are core elements in the disorders, characterizing both mania and depression and having recently been shown during euthymia. Several human genetic studies have implicated specific genes that make up the genesis of circadian rhythms in the manifestation of mood disorders with polymorphisms in molecular clock genes not only showing an association with the disorder but having also been linked to its phenotypic particularities. Many medications used to treat the disorder, such as antidepressant and mood stabilizers, affect the circadian clock. Finally, circadian rhythms and sleep researches have been the starting point of the developing of chronobiological therapies. These interventions are safe, rapid and effective and they should be considered first-line strategies for bipolar depression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.