ReviewCurrent neurology and neuroscience reports2015
A Clinical Approach to the Differential Diagnosis of Multiple Sclerosis.
Review in Current neurology and neuroscience reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- Genetic Risk in Multiple Sclerosis: Susceptibility, Modifiers and Unresolved Questions.Neurology and therapy · 2026Review
- Rare variation in neurological disease genes and its role in multiple sclerosis mimicry and phenotype.Genome medicine · 2025Article
- Case Study of an Unusual Intracranial Mesenchymal Neoplasm.Neurosurgery practice · 2025Article
- Case Report: Hypothalamic demyelinating lesion preceding lymphoma arising outside the central nervous system.Frontiers in oncology · 2025Article
- The dilemma of bright spots detected on magnetic resonance imaging of the brain for the diagnosis of multiple sclerosis: A retrospective evaluation of nonspecific white matter lesions.Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi · 2024Article
- Classification of neurological diseases using multi-dimensional CSF analysis.Brain : a journal of neurology · 2021Article
- BOLD signal within and around white matter lesions distinguishes multiple sclerosis and non-specific white matter disease: a three-dimensional approach.Journal of neurology · 2020Article
- Molecular Biomarkers in Multiple Sclerosis and Its Related Disorders: A Critical Review.International journal of molecular sciences · 2020Review
- The "central vein sign" in patients with diagnostic "red flags" for multiple sclerosis: A prospective multicenter 3T study.Multiple sclerosis (Houndmills, Basingstoke, England) · 2020Article
- Misdiagnosis of multiple sclerosis: Impact of the 2017 McDonald criteria on clinical practice.Neurology · 2019Review
- The current role of MRI in differentiating multiple sclerosis from its imaging mimics.Nature reviews. Neurology · 2018Review
- Headache and Its Management in Patients With Multiple Sclerosis.Current treatment options in neurology · 2018Review
- The tension between early diagnosis and misdiagnosis of multiple sclerosis.Nature reviews. Neurology · 2017Review
- MRI evaluation of thalamic volume differentiates MS from common mimics.Neurology(R) neuroimmunology & neuroinflammation · 2017Article
- Serum Glutamate Is a Predictor for the Diagnosis of Multiple Sclerosis.TheScientificWorldJournal · 2017Article
- Article
- Multiple sclerosis-like diagnosis as a complication of previously treated malaria in an iron and vitamin D deficient Nigerian patient.Metabolic brain disease · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnostic criteria for multiple sclerosis (MS) rely on clinical, paraclinical, and radiographic findings of limited specificity. Many disorders mimic MS, and the decision of when to investigate an alternative diagnosis can be challenging. Reliance on extensive ancillary testing to exclude potential mimics, however, is unnecessary in most cases. Rather, recognition and rigorous interpretation of "classic" clinical and radiographic features of MS are often sufficient to establish the diagnosis. Misinterpretation of the clinical and radiographic diagnostic criteria for MS in the setting of more common diseases and syndromes and a lack of vigilance for "red flags" are important contributors to misdiagnosis. A clinical framework for the differential diagnosis of MS that emphasizes phenotypes atypical for MS and suggests diseases or syndromes in which they more commonly occur may be an important diagnostic guide for clinicians in contemporary practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.