Evidence map›Paper›PMID 26112744›Full record

ReviewInfection2016

Hepatitis E virus in the countries of the Middle East and North Africa region: an awareness of an infectious threat to blood safety.

Soha Yazbek, Khalil Kreidieh, Sami Ramia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The global epidemiology of hepatitis E virus infection: A systematic review and meta-analysis.Liver international : official journal of the International Association for the Study of the Liver · 2020
    Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Co-infection of hepatitis E virus,Frontiers in cellular and infection microbiology · 2023
    Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Epidemiology of hepatitis E virus in Iran.World journal of gastroenterology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Soha YazbekDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.
Khalil KreidiehDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.
Sami RamiaDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon. sramia@aub.edu.lb.
American University of Beirut · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHepatitis E virus (HEV) is mainly transmitted through contaminated water supplies which make the virus endemic in developing countries including countries of the Middle East and North Africa (MENA) region. Recent reports suggest potential risk of HEV transmission via blood transfusion.

methodsRelated articles on HEV were collected by searching through the 25 countries of the MENA region using Pubmed and Medline within the past 14 years: January 2000-August 2014.

resultsOne hundred articles were extracted, of which 25 were not eligible. The articles discussed the seroprevalence of HEV and HEV markers in 12 countries. Eight articles provided data on HEV in blood donors. The seroprevalence of HEV in the general MENA population ranged from 2.0 to 37.5% and was higher in males than in females. Prevalence increased with age, but exposure seems to be in early life.

conclusionsIn the MENA region, the role of HEV as an infectious threat to blood safety is under-investigated. More data are needed to quantify the risk of transmission and to assess clinical outcomes. This requires, at least, surveillance screening of donors and recipients for HEV markers using sensitive and specific serological tests. At the present time, serious consideration should be given to selective screening for certain groups of patients (e.g., immunocompromised, pregnant women and others) who commonly require blood transfusion and are at high risk of hepatic failure or chronicity from HEV infection.

Indexed as

Blood SafetyAfrica, NorthernAwarenessBloodHepatitis EHepatitis E virusHumansMiddle EastSeroepidemiologic StudiesBlood donorsBlood safetyEpidemiologyHepatitis EHEVMENA region

Identifiers

PMID26112744
OpenAlexW773836082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.