ArticleJournal of neuroscience methods2015
Non-invasive primate head restraint using thermoplastic masks.
Article in Journal of neuroscience methods, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Reversed functional gradient in primate prefrontal cortex: Posterior dominance and frontopolar task-related deactivation.Science advances · 2026Article
- Human-relevant transcranial magnetic stimulation in awake rhesus macaques assisted by a non-invasive head and arm fixation apparatus.iScience · 2026Article
- Distinct neural geometries for target position and velocity in the primate superior colliculus.bioRxiv : the preprint server for biology · 2026Article
- Microendoscopic calcium imaging in motor cortices of macaques during rest and movement.iScience · 2025Article
- Home-Cage Training for Non-Human Primates: An Opportunity to Reduce Stress and Study Natural Behavior in Neurophysiology Experiments.Animals : an open access journal from MDPI · 2025Review
- A 3D-Printed helmet for precise and repeatable neuromodulation targeting in awake non-human primates.Heliyon · 2024Article
- Changes in neural readout of response magnitude during auditory streaming do not correlate with behavioral choice in the auditory cortex.Cell reports · 2023Article
- Cycles of goal silencing and reactivation underlie complex problem-solving in primate frontal and parietal cortex.Nature communications · 2023Article
- Rapid Input-Output Transformation between Local Field Potential and Spiking Activity during Sensation but not Action in the Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Pupillometry to Assess Auditory Sensation in Guinea Pigs.Journal of visualized experiments : JoVE · 2023Article
- Updates to the guinea pig animal model for in-vivo auditory neuroscience in the low-frequency hearing range.Hearing research · 2022Article
- Using non-invasive neuroimaging to enhance the care, well-being and experimental outcomes of laboratory non-human primates (monkeys).NeuroImage · 2021Review
- A novel rabbit fixator made of a thermoplastic mask for awake imaging experiments.Scientific reports · 2021Article
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- Non-invasive Eye Tracking Methods for New World and Old World Monkeys.Frontiers in behavioral neuroscience · 2019Article
- Sensorimotor transformation elicits systematic patterns of activity along the dorsoventral extent of the superior colliculus in the macaque monkey.Communications biology · 2019Article
- Improved methods for acrylic-free implants in nonhuman primates for neuroscience research.Journal of neurophysiology · 2017Article
- Individually customisable non-invasive head immobilisation system for non-human primates with an option for voluntary engagement.Journal of neuroscience methods · 2016Article
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Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundThe success of many neuroscientific studies depends upon adequate head fixation of awake, behaving animals. Typically, this is achieved by surgically affixing a head-restraint prosthesis to the skull. NEW
methodHere we report the use of thermoplastic masks to non-invasively restrain monkeys' heads. Mesh thermoplastic sheets become pliable when heated and can then be molded to an individual monkey's head. After cooling, the custom mask retains this shape indefinitely for day-to-day use.
resultsWe successfully trained rhesus macaques (Macaca mulatta) to perform cognitive tasks while wearing thermoplastic masks. Using these masks, we achieved a level of head stability sufficient for high-resolution eye-tracking and intracranial electrophysiology. COMPARISON WITH EXISTING
methodCompared with traditional head-posts, we find that thermoplastic masks perform at least as well during infrared eye-tracking and single-neuron recordings, allow for clearer magnetic resonance image acquisition, enable freer placement of a transcranial magnetic stimulation coil, and impose lower financial and time costs on the lab.
conclusionsWe conclude that thermoplastic masks are a viable non-invasive form of primate head restraint that enable a wide range of neuroscientific experiments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.