ReviewJournal of the American College of Cardiology2015
Finding the Gatekeeper to the Cardiac Catheterization Laboratory: Coronary CT Angiography or Stress Testing?
Review in Journal of the American College of Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of mid- to long-term clinical outcomes between anatomical testing and usual care in patients with suspected coronary artery disease: A meta-analysis of randomized trials.Clinical cardiology · 2017Pooled it
- Evaluation of the clinical value of CCTA as the preferred screening method in patients with chronic coronary syndrome.BMC cardiovascular disorders · 2025Trial
- Diagnostic yield and accuracy of coronary CT angiography after abnormal nuclear myocardial perfusion imaging.Scientific reports · 2018Trial
- Exploring the prediction model and core genes for coronary artery disease in non-obese steatotic liver disease patients.Frontiers in medicine · 2026Article
- Coronary computed tomography angiographyWorld journal of cardiology · 2025Article
- Bibliometric analysis of CT-based atherosclerosis plaque imaging in coronary artery disease: from "gatekeeper" of invasive angiography to "whistleblower" of high-risk patients.Quantitative imaging in medicine and surgery · 2025Article
- Comparison of magnetocardiography and coronary computed tomographic angiography for detection of coronary artery stenosis and the influence of calcium.European radiology · 2025Article
- The Long March to Identify Patients With Coronary Artery Disease by Pretest Probability Model.JACC. Asia · 2025Article
- Identification of biomarkers associated with coronary artery disease and non-alcoholic fatty liver disease by bioinformatics analysis and machine learning.Scientific reports · 2025Article
- Comprehensive Analysis of Cardiovascular Diseases: Symptoms, Diagnosis, and AI Innovations.Bioengineering (Basel, Switzerland) · 2024Review
- Predicting major adverse cardiovascular events within 3 years by optimization of radiomics model derived from pericoronary adipose tissue on coronary computed tomography angiography: a case-control study.BMC medical imaging · 2024Article
- The role of early-phase trials and real-world evidence in drug development.Nature cardiovascular research · 2024Review
- Radiomics applications in cardiac imaging: a comprehensive review.La Radiologia medica · 2023Review
- Review
- Atherosclerosis Imaging Quantitative Computed Tomography (AI-QCT) to guide referral to invasive coronary angiography in the randomized controlled CONSERVE trial.Clinical cardiology · 2023Article
- Nationwide Trends of Gatekeeper to Invasive Coronary Angiography in Suspected Coronary Artery Disease.Korean circulation journal · 2022Article
- Relationship of age, atherosclerosis and angiographic stenosis using artificial intelligence.Open heart · 2021Article
- The Multidimensionality of Coronary Artery Disease: Combining, Conflating and Changing.JACC. Asia · 2021Article
- Cardiac Computed Tomography Radiomics for the Non-Invasive Assessment of Coronary Inflammation.Cells · 2021Review
- Added Value of Transluminal Attenuation Gradient to Qualitative CCTA Ischemia Detection as Determined byDiagnostics (Basel, Switzerland) · 2020Article
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4 authors.
Funding
Abstract
Functional capacity is a robust predictor of clinical outcomes, and stress testing is used in current practice paradigms to guide referral to invasive coronary angiography. However, invasive coronary angiography is driven by ongoing symptoms, as well as risk of adverse outcomes. The limitations of current functional testing-based paradigms might be avoided by using coronary computed tomographic angiography (CCTA) for exclusion of obstructive coronary artery disease. The growth of CCTA has been supported by comparative prognostic evidence with CCTA and functional testing, as well as radiation dose reduction. Use of CCTA for physiological evaluation of coronary lesion-specific ischemia may facilitate evaluation of moderate stenoses, designation of the culprit lesion, and prediction of benefit from revascularization. The potential of CCTA to serve as an effective gatekeeper to invasive coronary angiography will depend, in part, on the adoption of these new developments, as well as definition of the benefit of detecting high-risk plaque for guiding the management of selected patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.