ReviewMolecules (Basel, Switzerland)2015
Progress in Studies on Rutaecarpine. II.--Synthesis and Structure-Biological Activity Relationships.
Review in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 67 citations in OpenAlex.
- Article
- Beyond anti-inflammatory strategies: Epigenetic targets as emerging therapeutic frontiers in acute pancreatitis.World journal of gastroenterology · 2026Article
- Optimization of callus culture for enhanced rutaecarpine and evodiamine accumulation inFrontiers in plant science · 2026Article
- Rutaecarpine Protects Human Endothelial Cells from Oxidative-Stress-Induced Apoptosis via TRPV1- and AhR-Mediated Nrf2 Activation.Antioxidants (Basel, Switzerland) · 2025Article
- Computational Docking as a Tool in Guiding the Drug Design of Rutaecarpine Derivatives as Potential SARS-CoV-2 Inhibitors.Molecules (Basel, Switzerland) · 2024Article
- Evodiamine ameliorates intervertebral disc degeneration through the Nrf2 and MAPK pathways.Cytotechnology · 2024Article
- Diversity oriented total synthesis (DOTS) of pyridoquinazolinone alkaloids and their analogues.Tetrahedron chem · 2024Article
- Rutaecarpine Mitigates Cognitive Impairment by Balancing Mitochondrial Function Through Activation of the AMPK/PGC1α Pathway.Molecular neurobiology · 2023Article
- Promising derivatives of rutaecarpine with diverse pharmacological activities.Frontiers in chemistry · 2023Review
- Natural products in attenuating renal inflammationFrontiers in immunology · 2023Review
- Evodiamine and Rutaecarpine as Potential Anticancer Compounds: A Combined Computational Study.International journal of molecular sciences · 2022Article
- Time effect of rutaecarpine on caffeine pharmacokinetics in rats.Biochemistry and biophysics reports · 2021Article
- Role of Chinese Herbal Medicines in Regulation of Energy Metabolism in Treating Cardiovascular Diseases.Chinese journal of integrative medicine · 2019Review
- Rutacecarpine Inhibits Angiogenesis by Targeting the VEGFR2 and VEGFR2-Mediated Akt/mTOR/p70s6k Signaling Pathway.Molecules (Basel, Switzerland) · 2018Article
- Ethanol Extract ofNutrients · 2018Article
- Plant Alkaloids as Antiplatelet Agent: Drugs of the Future in the Light of Recent Developments.Frontiers in pharmacology · 2016Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rutaecarpine is a pentacyclic indolopyridoquinazolinone alkaloid found in Evodia rutaecarpa and other related herbs. It has a variety of intriguing biological properties, which continue to attract the academic and industrial interest. Studies on rutaecarpine have included isolation from new natural sources, development of new synthetic methods for its total synthesis, the discovery of new biological activities, metabolism, toxicology, and establishment of analytical methods for determining rutaecarpine content. The present review focuses on the synthesis, biological activities, and structure-activity relationships of rutaecarpine derivatives, with respect to their antiplatelet, vasodilatory, cytotoxic, and anticholinesterase activities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.