SynthesisThe British journal of radiology2015
Diagnostic performance of diffusion-weighted MRI for detection of pelvic metastatic lymph nodes in patients with cervical cancer: a systematic review and meta-analysis.
Synthesis in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Different imaging techniques for the detection of pelvic lymph nodes metastasis from gynecological malignancies: a systematic review and meta-analysis.Oncotarget · 2017Pooled it
- Diagnostic utility of apparent diffusion coefficient values in cervical cancer staging: A retrospective study.European journal of radiology open · 2026Article
- Diagnostic performance of quantitative measures from [European journal of nuclear medicine and molecular imaging · 2026Article
- Multimodal imaging of cervical lymphadenopathy: diagnostic value and clinical applications.Medicine and pharmacy reports · 2025Review
- Reliability study of MRI in detecting lymph node metastasis of cervical cancer: a multi-center retrospective study result analysis.Quantitative imaging in medicine and surgery · 2025Article
- Article
- Magnetic Resonance Imaging in the Management of Women with Low-Risk Early-Stage Cervical Cancer: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Outcomes of Laparoscopic Radical Hysterectomy in Ia1-Ib1 Cervical Cancer Patients: A Multi-Center Study with 10 Years' Experiences in the Real World.Annals of surgical oncology · 2025Article
- Comments on "MRI andPolish journal of radiology · 2025Article
- Endometrial Cancer: A Daily Clinical Practice Guide for Radiologists.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Review
- The Role of Imaging in Cervical Cancer Staging: ESGO/ESTRO/ESP Guidelines (Update 2023).Cancers · 2024Review
- Diagnostic accuracy of MRI, CT, and [Insights into imaging · 2024Article
- The value of multiparameter MRI of early cervical cancer combined with SCC-Ag in predicting its pelvic lymph node metastasis.Frontiers in oncology · 2024Article
- Lymph node assessment in cervical cancer: current approaches.Frontiers in oncology · 2024Review
- Impact of Image Enhancement on the Radiomics Stability of Diffusion-Weighted MRI Images of Cervical Cancer.Cureus · 2024Article
- Staging of Cervical Cancer: A Practical Approach Using MRI and FDG PET.AJR. American journal of roentgenology · 2023Review
- Texture Analysis in Uterine Cervix Carcinoma: Primary Tumour and Lymph Node Assessment.Diagnostics (Basel, Switzerland) · 2023Article
- Clinical value of conventional magnetic resonance imaging combined with diffusion-weighted imaging in predicting pelvic lymph node metastasis of cervical cancer.Frontiers in oncology · 2023Article
- Value of MRI and diffusion-weighted imaging in diagnosing normal-sized pelvic lymph nodes metastases in patients with cervical cancer.The British journal of radiology · 2022Article
- Utility of 3T MRI in Women with IB1 Cervical Cancer in Determining the Necessity of Less Invasive Surgery.Cancers · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, diffusion-weighted (DW) MRI has emerged as a new technique for detecting the pelvic lymph metastases in patients with cervical cancer. The aim of this meta-analysis was to assess the diagnostic value of DW imaging (DWI) for benign/malignant discrimination of pelvic lymph nodes (LNs). Studies about DWI for the detection of metastatic LNs were searched in the PubMed, EMBASE, Web of Science, EBSCO, the Cochrane Library and three Chinese databases. Based on the extracted data, we determined pooled sensitivities, specificities and diagnostic odds ratios (DORs) across studies, calculated positive and negative likelihood ratios (LRs) and constructed summary receiver operating characteristic curves with area under the curve (AUC) and Q* obtained. We also analysed the heterogeneity between studies based on subgroup analysis, threshold effect and publication bias. In total, 15 studies involving 1021 patients met the inclusion criteria. The pooled sensitivity, specificity and DOR of DWI were 0.86 [95% confidence interval (CI), 0.84-0.89], 0.84 (95% CI, 0.83-0.86) and 47.21 (95% CI, 25.67-86.81), respectively. LR syntheses yielded overall positive LR of 6.55 (95% CI, 4.77-9.01) and negative LR of 0.17 (95% CI, 0.12-0.23). The AUC and Q* index were 0.9384 and 0.8754, respectively. The heterogeneity was relatively high between studies; however, there was no evidence for threshold effect and publication bias. DWI is beneficial in the pelvic nodal assessment in patients with cervical cancer. Large-scale, high-quality trials with standard protocols are required to evaluate its clinical value for discrimination of metastatic from non-metastatic pelvic LNs in patients with cervical cancer. Advances in knowledge include providing evidence to assess the role of DWI in nodal staging of cervical cancer.
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