Evidence map›Paper›PMID 26110495›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2015

Response to thyrotropin-releasing hormone stimulation tests in preterm infants with transient hypothyroxinemia of prematurity.

A Yamamoto, M Kawai, K Iwanaga, T Matsukura, F Niwa, T Hasegawa, T Heike

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Screening and management of thyroid dysfunction in preterm infants.Annals of pediatric endocrinology & metabolism · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A YamamotoDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
M KawaiDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
K IwanagaDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
T MatsukuraDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
F NiwaDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
T HasegawaDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
T HeikeDepartment of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWhether hormone supplementation is necessary for infants with transient hypothyroxinemia of prematurity (THOP) remains controversial, and further analysis of the hypothalamus-pituitary-thyroid axis of infants with THOP is necessary. STUDY

designThyrotropin-releasing hormone (TRH) stimulation tests were performed at 2 weeks of age in 50 infants with a gestational age of 30 weeks or less, and the data were analyzed retrospectively.

resultSubjects were divided into three groups; group A consisted of euthyroid infants, group B consisted of infants with THOP and group C consisted of hypothyroid infants. The basal and peak thyroid-stimulating hormone level of group C in response to TRH stimulation tests was significantly higher than the others, but no differences were observed between groups A and B.

conclusionThe response of infants with THOP to the TRH stimulation test was not different from that of euthyroid infants, which suggested that their hypothalamic-pituitary-thyroid axis was appropriately regulated in infants with THOP.

Indexed as

HypothyroidismInfant, Premature, DiseasesThyrotropin-Releasing HormoneFemaleHormone Replacement TherapyHormonesHumansInfantInfant, NewbornInfant, PrematureJapanMaleMonitoring, PhysiologicRetrospective StudiesStimulation, ChemicalThyrotropinHormonesThyrotropinThyrotropin-Releasing HormoneThyroxine

Identifiers

PMID26110495

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.