Evidence map›Paper›PMID 26110253›Full record

ArticleNutrients2015

A Novel Approach to Improving Fat Delivery in Neonatal Enteral Feeding.

Jane Jarjour, Alexa M Juarez, Denizen K Kocak, Nathan J Liu, Mika M Tabata, Keli M Hawthorne, Renata F Ramos, Steven A Abrams

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Jane JarjourDepartment of Bioengineering, Rice University, Houston, TX 77005, USA. jane.jarjour@alumni.rice.edu.
Alexa M JuarezDepartment of Bioengineering, Rice University, Houston, TX 77005, USA. juarezam@ymail.com.
Denizen K KocakDepartment of Bioengineering, Rice University, Houston, TX 77005, USA. Denizen.Kocak@utsouthwestern.edu.
Nathan J LiuDepartment of Bioengineering, Rice University, Houston, TX 77005, USA. teamnutriflow@gmail.com.
Mika M TabataDepartment of Bioengineering, Rice University, Houston, TX 77005, USA. tabata@alumni.rice.edu.
Keli M HawthorneSection of Neonatology, Department of Pediatrics, The University of Texas at Austin Dell Medical School, Austin, TX 77030, USA. keli.hawthorne@austin.utexas.edu.
Renata F RamosDepartment of Bioengineering, Rice University, Houston, TX 77005, USA. rfr1@rice.edu.
Steven A AbramsSection of Neonatology, Department of Pediatrics, The University of Texas at Austin Dell Medical School, Austin, TX 77030, USA. sabrams@austin.utexas.edu.
Rice University · USThe University of Texas at Austin · USBaylor College of Medicine · USStanford University · USThe University of Texas Southwestern Medical Center · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Continuous infusion systems used for enteral nutrition support in the neonatal intensive care unit deliver as little as 60% of the fat in human milk to the neonate. This study determined the effect of mixing common feedings for preterm infants in the feeding bag and tubing on fat losses during enteral feeding. Laboratory models were developed to assess the contribution of various mixing techniques to delivered fat content. Fat content was measured periodically during feeding and compared to baseline measurements. A multistage approach incorporating a feeding bag inverter and a tubing circulation loop delivered >90% of milk fat when used in conjunction with a commercial continuous infusion system. With unfortified human milk, this approach delivered 91.9% ± 1.5% of fat content over a one hour feed, significantly greater (p < 0.01) than 77.5% ± 2.2% delivered by continuous infusion controls (Mean ± SEM). With fortified human milk, this approach delivered 92.1% ± 2.4% of fat content, significantly greater (p < 0.01) than 79.4% ± 1.0% delivered by a non-adapted infusion system (Mean ± SEM). Mixing human milk during continuous infusion improves fat delivery, which may improve nutrition and growth outcomes in low birth weight neonates.

Indexed as

Dietary FatsEnteral NutritionEquipment DesignFood, FortifiedHumansInfantInfant Nutritional Physiological PhenomenaInfant, PrematureInfant, Very Low Birth WeightIntensive Care Units, NeonatalMilk, HumanDietary Fatsbreast milkenteral nutritionhuman milk-derived fortifierneonatal intensive care unitsneonatesnutriflowvery low birth weight

Identifiers

PMID26110253
PMCPMC4488830
OpenAlexW2155615952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.