Evidence map›Paper›PMID 26109796›Full record

ReviewWorld journal of gastroenterology2015

Food allergy in irritable bowel syndrome: The case of non-celiac wheat sensitivity.

Pasquale Mansueto, Alberto D'Alcamo, Aurelio Seidita, Antonio Carroccio

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03027492 (Gynaecological Disorders in Patients With Not-celiac Wheat Sensitivity), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03027492 nacompletednot on this map

Gynaecological Disorders in Patients With Not-celiac Wheat Sensitivity

TypeinterventionalSponsorUniversity of PalermoRan2001 to 2025Enrolled500ConditionsNon-celiac Wheat SensitivityArmsGluten free diet, NCWS open challenge with wheat
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 64 citations in OpenAlex.

  1. Trial
  2. Observational
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  9. An Update on the Assessment and Management of Pediatric Abdominal Pain.Pediatric health, medicine and therapeutics · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pasquale MansuetoPasquale Mansueto, Alberto D'Alcamo, Aurelio Seidita, Antonio Carroccio, Biomedical Department of Internal Medicine and Specialist, University Hospital of Palermo, 90141 Palermo, Italy.
Alberto D'AlcamoPasquale Mansueto, Alberto D'Alcamo, Aurelio Seidita, Antonio Carroccio, Biomedical Department of Internal Medicine and Specialist, University Hospital of Palermo, 90141 Palermo, Italy.
Aurelio SeiditaPasquale Mansueto, Alberto D'Alcamo, Aurelio Seidita, Antonio Carroccio, Biomedical Department of Internal Medicine and Specialist, University Hospital of Palermo, 90141 Palermo, Italy.
Antonio CarroccioPasquale Mansueto, Alberto D'Alcamo, Aurelio Seidita, Antonio Carroccio, Biomedical Department of Internal Medicine and Specialist, University Hospital of Palermo, 90141 Palermo, Italy.
University of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders, having a prevalence of 12%-30% in the general population. Most patients with IBS attribute their symptoms to adverse food reactions. We review the role of diet in the pathogenesis of IBS and the importance of dietary factors in the management of these patients. The MEDLINE electronic database (1966 to Jan 2015) was searched using the following keywords: "food", "diet", "food allergy", "food hypersensitivity", "food intolerance", "IBS", "epidemiology", "pathogenesis", "pathophysiology", "diagnosis", "treatment". We found 153 eligible papers; 80 were excluded because: not written in English, exclusive biochemical and experimental research, case reports, reviews, and research otherwise not relevant to our specific interest. We selected 73 papers: 43 original papers, 26 reviews and 4 letters to the editor. These papers focused on IBS pathogenesis, the association between IBS and atopy, and between IBS and food allergy, the relationship between IBS and non-celiac wheat sensitivity, the role of diet in IBS. Pending further scientific evidence, a cautious approach is advisable but the concept of food allergy should be included as a possible cause of IBS, and a dietary approach may have a place in the routine clinical management of IBS.

Indexed as

Celiac DiseaseDietDiet, Gluten-FreeHumansIrritable Bowel SyndromePrevalenceRisk FactorsTreatment OutcomeWheat HypersensitivityAsthmaAtopyElimination dietFood allergyFood intoleranceIrritable bowel syndromeNon-celiac wheat sensitivity

Identifiers

PMID26109796
PMCPMC4476871
OpenAlexW2411642957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.