ArticlePharmacognosy research2015
Antioxidant and Antiacetylcholinesterase Activity of Teucrium hyrcanicum.
Article in Pharmacognosy research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Isolation and structure elucidation of the compounds from Teucrium hyrcanicum L. and the investigation of cytotoxicity, antioxidant activity, and protective effect on hydrogen peroxide-induced oxidative stress.BMC complementary medicine and therapies · 2023Article
- Anticholinesterase Activity of Selected Medicinal Plants from Navarra Region of Spain and a Detailed Phytochemical Investigation ofMolecules (Basel, Switzerland) · 2022Article
- HR-LCMS-Based Metabolite Profiling, Antioxidant, and Anticancer Properties ofAntioxidants (Basel, Switzerland) · 2020Article
- Investigation of phenolic compounds and antioxidant activity of leaves extracts from seventeen cultivars of Iranian olive (Journal of food science and technology · 2018Article
- Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review.Pain research & management · 2018Review
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Authors and funding
6 authors.
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Abstract
backgroundTeucrium hyrcanicum belonging to the Lamiaceae family is a native plant in Iran; it is called Maryam nokhodi-e-jangali in Farsi.
objectiveThe aim of this study is to evaluate acetylcholinesterase inhibition (AChEI), antioxidant activity and flavonoids content of T. hyrcanicum methanol extract. MATERIALS AND
methodsThe air-dried and the ground aerial parts of T. hyrcanicum were extracted by percolation method with methanol. Antioxidant activity of the extract was investigated by using 2,2'-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power assay (FRAP) methods. In addition, AChEI and flavonoid content of T. hyrcanicum methanol extract were measured.
resultsThe results showed that total flavonoid content of T. hyrcanicum in reference to the standard curve for quercetin was 20.70 ± 0.05 mg quercetin equivalents/g of extract. In the FRAP method, the antioxidant activity of T. hyrcanicum extract and butyl hydroxyanisole (BHA) (as a positive control) were 657.5 ± 0.04 and 880 ± 0.06 mmol Fe II/1 g dried extract. According to results of DPPH assay, half maximal inhibitory concentration (IC50) value for DPPH radical-scavenging activities of T. hyrcanicum methanol extract, vitamin E and BHA were 74.6, 14.12 and 7.8 μg/mL, respectively. IC50 value for AChEI of T. hyrcanicum and donepezil as a positive control were 2.12 mg/mL and 0.013 mg/mL.
conclusionThe results of the present study showed T. hyrcanicum is a natural antioxidant that the flavonoid content can be responsible for extract effects.
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