ArticleDiabetes care2015
Mismatch of Sleep and Work Timing and Risk of Type 2 Diabetes.
Article in Diabetes care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
100 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Chronotype differences in the risk of cancers, diabetes mellitus, and poor mental health among shift workers: a meta-analysis.Scandinavian journal of work, environment & health · 2026Pooled it
- Sleep features and the risk of type 2 diabetes mellitus: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Chronotype Differences in Energy Intake, Cardiometabolic Risk Parameters, Cancer, and Depression: A Systematic Review with Meta-Analysis of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Efficacy and Adherence to a Supervised Aerobic Exercise Training Intervention in Night-Shift Hospital Nurses: A Randomized Controlled Trial.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Trial
- Scheduled evening sleep and enhanced lighting improve adaptation to night shift work in older adults.Occupational and environmental medicine · 2016Trial
- Rotating Night Shift Work and Risk of Incident Cardiovascular Disease and Mortality by Chronotype: A Prospective Cohort Study in Nurses' Health Study II.medRxiv : the preprint server for health sciences · 2026Article
- Discovery of circadian clock activators with anti-obesity efficacy via suppression of adipocyte development and hypertrophy.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Overnight wakefulness impairs next-day postprandial glucose in young women independent of sex hormones.The Journal of clinical endocrinology and metabolism · 2026Article
- Quercetin and Fisetin activate circadian clock via RORα and inhibit adipocyte growth.bioRxiv : the preprint server for biology · 2026Article
- Chronotype, Life's Essential 8, and Risk of Cardiovascular Disease: A Prospective Cohort Study in UK Biobank.Journal of the American Heart Association · 2026Article
- Novel circadian clock activators display anti-obesity efficacy via suppression of adipocyte development and hypertrophy.bioRxiv : the preprint server for biology · 2026Article
- Elevated cardiometabolic risk markers in evening chronotype shift workers: a case-control study in male workers.The British journal of nutrition · 2025Article
- Temporal Patterns of Eating and Diet Composition of Night Shift Workers Are Influenced More by Shift Type than by Chronotype.Nutrients · 2025Article
- Continuous Glucose Monitoring in People at High Risk of Diabetes and Dysglycaemia: Transforming Early Risk Detection and Personalised Care.Life (Basel, Switzerland) · 2025Review
- Association between night shift work and markers of metabolism, cardiovascular and immune system in a population-based German cohort.GeroScience · 2025Article
- Mendelian randomization study of sleep traits and risk of colorectal cancer.Scientific reports · 2025Article
- Chronotype in relation to shift work: A cohort study among 37,731 female nurses.Journal of sleep research · 2025Article
- Modified Cortisol Circadian Rhythm: The Hidden Toll of Night-Shift Work.International journal of molecular sciences · 2025Review
- Cross-sectional relationships of circadian misalignment and rest-activity rhythms with occupational attainment in UK Biobank participants.Chronobiology international · 2025Article
- The Role of the Chronotype in Developing an Excessive Body Weight and Its Complications-A Narrative Review.Nutrients · 2024Review
40 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo examine whether a mismatch between chronotype (i.e., preferred sleep timing) and work schedule is associated with type 2 diabetes risk. RESEARCH DESIGN AND
methodsIn the Nurses' Health Study 2, we followed 64,615 women from 2005 to 2011. Newly developed type 2 diabetes was the outcome measure (n = 1,452). A question on diurnal preference ascertained chronotype in 2009; rotating night shift work exposure was assessed regularly since 1989.
resultsCompared with intermediate chronotypes, early chronotypes had a slightly decreased diabetes risk after multivariable adjustment (odds ratio 0.87 [95% CI 0.77-0.98]), whereas no significant association was observed for late chronotypes (1.04 [0.89-1.21]). Among early chronotypes, risk of type 2 diabetes was modestly reduced when working daytime schedules (0.81 [0.63-1.04]) and remained similarly reduced in women working <10 years of rotating night shifts (0.84 [0.72-0.98]). After ≥10 years of shift work exposure, early chronotypes had a nonsignificant elevated diabetes risk (1.15 [0.81-1.63], Ptrend = 0.014). By contrast, among late chronotypes, the significantly increased diabetes risk observed among day workers (1.51 [1.13-2.02]) appeared largely attenuated if their work schedules included night shifts (<10 years: 0.93 [0.76-1.13]; ≥10 years: 0.87 [0.56-1.34]; Ptrend = 0.14). The interaction between chronotype and shift work exposure was significant (Pinteraction = 0.0004). Analyses restricting to incident cases revealed similar patterns.
conclusionsIn early chronotypes, type 2 diabetes risk increased with increasing duration of shift work exposure, whereas late types had the highest diabetes risk working daytime schedules. These data add to the growing body of evidence that workers could benefit from shift schedules minimizing interference with chronotype-dependent sleep timing.
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