Evidence map›Paper›PMID 26108804›Full record

ArticleJournal of cardiac surgery2015

Acute kidney injury following surgical aortic valve replacement.

Marc Najjar, Halit Yerebakan, Robert A Sorabella, Denis J Donovan, Alexander P Kossar, Sowmyashree Sreekanth, Paul Kurlansky, Michael A Borger, Michael Argenziano, Craig R Smith and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiac surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Observational
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  7. Article
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  9. Article
  10. TAVR-present, future, and challenges in developing countries.Indian journal of thoracic and cardiovascular surgery · 2019
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marc NajjarNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Halit YerebakanNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Robert A SorabellaNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Denis J DonovanNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Alexander P KossarNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Sowmyashree SreekanthNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Paul KurlanskyNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Michael A BorgerNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Michael ArgenzianoNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Craig R SmithNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.
Isaac GeorgeNew York Presbyterian Hospital - College of Physicians and Surgeons of Columbia University, New York, New York.

Funding

Training Medical Students in NIDDK ResearchT35DK093430 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI QAIS AL-AWQATI, Utpal Pajvani · 2012 to 2026
$1.3M
NIDDK NIH HHS T35 DK093430
6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is a significant complication of surgical aortic valve replacement (SAVR). This study sought to describe AKI following SAVR, its risk factors, predictors and effect on long-term survival.

methodsWe retrospectively reviewed 2169 patients who underwent isolated SAVR between 2000 and 2012. The main end-points were occurrence of AKI, postoperative complications, and short- and long-term survival rates following SAVR. Patients were divided into two groups: AKI+ (n = 181) and AKI- (n = 1945).

resultsAKI occurred in 8.5% of patients, of which 3.9% (n = 7) needed dialysis. Predictors of AKI after SAVR were body mass index (BMI) and intraoperative packed red blood cells (PRBC) transfusion. AKI+ patients had a more complicated postoperative course and higher cumulative mortality (25% vs. 17%, p = 0.012) with a median follow-up of 4.1 years. AKI was not found to be an independent predictor of mortality.

conclusionsPredictors of AKI after SAVR are increased BMI and intraoperative PRBC transfusion. AKI conferred an increase in hospital length of stay and cumulative mortality while the need for postoperative dialysis was associated with the most complicated hospital stays and the highest in-hospital and cumulative mortalities; therefore careful recognition of patients at risk of AKI is warranted for a better preoperative renal optimization. However, incidence of AKI was lower than what is reported after both on-CPB cardiac surgeries and transcatheter aortic valve replacement, moreover AKI was not found to be an independent predictor of mortality.

Indexed as

Acute Kidney InjuryHeart Valve Prosthesis ImplantationPostoperative ComplicationsAgedAged, 80 and overAortic ValveBicuspid Aortic Valve DiseaseBody Mass IndexDialysisErythrocyte TransfusionFemaleForecastingHeart Defects, CongenitalHeart Valve DiseasesHospital MortalityHumans

Identifiers

PMID26108804
PMCPMC5531286

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.