ArticleOrganic & biomolecular chemistry2015
A platform for efficient, thiol-stable conjugation to albumin's native single accessible cysteine.
Article in Organic & biomolecular chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed.
- Article
- Creating unimolecular multivalent diversity in protein conjugates via the Passerini multicomponent bioconjugation with isocyanoproteins.Communications chemistry · 2026Article
- Antimicrobial Peptides: Current Status, Mechanisms of Action, and Strategies to Overcome Therapeutic Limitations.Microorganisms · 2025Review
- Article
- Conjugation of Antibodies and siRNA Duplexes to Polymer Nanoparticles via Maleimide-Thiol Chemistry.ACS omega · 2024Article
- Fixation and Visualization of Full Protein Corona on Lipid Surface of Composite Nanoconstruction.Nanomaterials (Basel, Switzerland) · 2023Article
- Intramolecular thiomaleimide [2 + 2] photocycloadditions: stereoselective control for disulfide stapling and observation of excited state intermediates by transient absorption spectroscopy.Chemical science · 2022Article
- The renaissance of chemically generated bispecific antibodies.Nature reviews. Chemistry · 2021Review
- One-pot thiol-amine bioconjugation to maleimides: simultaneous stabilisation and dual functionalisation.Chemical science · 2020Article
- An Overview of Antibody Conjugated Polymeric Nanoparticles for Breast Cancer Therapy.Pharmaceutics · 2020Review
- A new class of recombinant human albumin with multiple surface thiols exhibits stable conjugation and enhanced FcRn binding and blood circulation.The Journal of biological chemistry · 2019Article
- Site-specific chelator-antibody conjugation for PET and SPECT imaging with radiometals.Drug discovery today. Technologies · 2018Review
- Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
- Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin.The Journal of biological chemistry · 2017Article
- Site-Selective Disulfide Modification of Proteins: Expanding Diversity beyond the Proteome.Chemistry (Weinheim an der Bergstrasse, Germany) · 2016Review
- Diazaoxatriangulenium: synthesis of reactive derivatives and conjugation to bovine serum albumin.Organic & biomolecular chemistry · 2016Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Herein we report the use of bromomaleimides for the construction of stable albumin conjugates via conjugation to its native, single accessible, cysteine followed by hydrolysis. Advantages over the classical maleimide approach are highlighted in terms of quantitative hydrolysis and absence of undesirable retro-Michael deconjugation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.