ArticleBMC health services research2015
Risk factors for loss to follow-up prior to ART initiation among patients enrolling in HIV care with CD4+ cell count ≥200 cells/μL in the multi-country MTCT-Plus Initiative.
Article in BMC health services research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 24 citations in OpenAlex.
- Predictors of Retention in HIV Care Among Youth (15-24) in a Universal Test-and-Treat Setting in Rural Kenya.Journal of acquired immune deficiency syndromes (1999) · 2017Trial
- Prevalence, trend and risk factors for antiretroviral therapy discontinuation among HIV-infected adults in Ethiopia in 2003-2015.PloS one · 2017Trial
- Antiretroviral treatment outcomes and survival pattern of people living with HIV in Bauchi State, Nigeria.PloS one · 2025Article
- Determinants of Loss to Follow Up Among Adult People Living with HIV Enrolled in Antiretroviral Therapy in West Wollega Public Hospitals, Oromia, Ethiopia.HIV/AIDS (Auckland, N.Z.) · 2024Article
- Risk factors for interruption in treatment among HIV-infected adolescence attending health care and treatment clinics in Tanzania.AIDS research and therapy · 2023Article
- Predictors of loss to follow up from antiretroviral therapy among adolescents with HIV/AIDS in Tanzania.PloS one · 2022Article
- Timing of HIV diagnosis relative to pregnancy and postpartum HIV care continuum outcomes among Latin American women, 2000 to 2017.Journal of the International AIDS Society · 2021Article
- Challenges with tracing patients on antiretroviral therapy who are late for clinic appointments in rural South Africa and recommendations for future practice.Global health action · 2020Article
- High viral suppression and low attrition in healthy HIV-infected patients initiated on ART with CD4 above 500 cells/µL in a program setting in Uganda.African health sciences · 2020Article
- Long-term retention on antiretroviral therapy among infants, children, adolescents and adults in Malawi: A cohort study.PloS one · 2019Article
- Article
- Risk factors and reasons for treatment abandonment among children with lymphoma in Malawi.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
- Association between pregnancy at enrollment into HIV care and loss to care among women in the Democratic Republic of Congo, 2006-2013.PloS one · 2018Article
- Observational Study of the Effect of Patient Outreach on Return to Care: The Earlier the Better.Journal of acquired immune deficiency syndromes (1999) · 2017Observational
- Progress Toward Achieving the UNAIDS 90-90-90 Goals in HIV Care From Diagnosis to Durable Viral Suppression in the Country of Georgia.AIDS research and human retroviruses · 2017Article
- Lost to follow-up: failure to engage children in care in the first three months of diagnosis.AIDS care · 2016Article
- CD4 Variability in Malawi: Implications for Use of a CD4 Threshold of 500 Cells/mmOpen forum infectious diseases · 2016Article
- HIV Care and Treatment Beliefs among Patients Initiating Antiretroviral Treatment (ART) in Oromia, Ethiopia.AIDS and behavior · 2016Article
- Loss to follow-up among youth accessing outpatient HIV care and treatment services in Kisumu, Kenya.AIDS care · 2016Article
- Reducing Mother-to-Child Transmission of HIV Using Quality Improvement Approaches.Journal of the International Association of Providers of AIDS CareArticle
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundIn resource-limited settings, many HIV-infected patients are lost to follow-up (LTF) before starting ART; risk factors among those not eligible for ART at enrollment into care are not well described.
methodsWe examined data from 4,278 adults (3,613 women, 665 men) enrolled in HIV care through March 2007 in the MTCT-Plus Initiative with a CD4 count ≥200 cells/mm(3) and WHO stage ≤ 2 at enrollment. Patients were considered LTF if > 12 months elapsed since their last clinic visit. Gender-specific Cox regression models were used to assess LTF risk factors.
resultsThe proportion LTF was 8.2 % at 12 months following enrollment, and was higher among women (8.4 %) than men (7.1 %). Among women, a higher risk of LTF was associated with younger age (adjusted hazard ratio [AHR]15-19/30+: 2.8, 95 % CI:2.1-3.6; AHR20-24/30+:1.9, 95 % CI:1.7-2.2), higher baseline CD4 count (AHR350-499/200-349:1.5; 95 % CI:1.0-2.1; AHR500+/200-349:1.5; 95 % CI:1.0-2.0), and being pregnant at the last clinic visit (AHR:1.9, 95 % CI:1.4-2.5). Factors associated with a lower risk of LTF included, employment outside the home (AHR:0.73, 95 % CI:0.59-0.90), co-enrollment of a family/household member (AHR:0.40, 95 % CI:0.26-0.61), and living in a household with ≥4 people (AHR:0.74, 95 % CI:0.64-0.85). Among men, younger age (AHR15-19/30+: 2.1, 95 % CI:1.2-3.5 and AHR30-34/35+:1.5, 95 % CI:1.0-2.4) had a higher risk of LTF. Electricity in the home (AHR:0.61, 95 % CI:0.41-0.91) and living in a household with ≥4 people (AHR:0.58, 95 % CI:0.39-0.85) had a lower risk of LTF.
conclusionsSocio-economic status and social support may be important determinants of retention in patients not yet eligible for ART. Among women of child-bearing age, strategies around sustaining HIV care during and after pregnancy require attention.
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