Evidence map›Paper›PMID 26107951›Full record

ArticlePloS one2015

Use of Approximate Bayesian Computation to Assess and Fit Models of Mycobacterium leprae to Predict Outcomes of the Brazilian Control Program.

Rebecca Lee Smith, Yrjö Tapio Gröhn

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rebecca Lee SmithDepartment of Pathobiology, University of Illinois College of Veterinary Medicine, Urbana, Illinois, United States of America.
Yrjö Tapio GröhnDepartment of Population Medicine and Diagnostic Science, Cornell University College of Veterinary Medicine, Ithaca, New York, United States of America.

Funding

Mathematical and Statistical Modeling of Mycobacterial Disease ControlK01OD010968 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SMITH, REBECCA LEE · 2012 to 2015
$285k
NIH HHS 8K01OD010968-03NIH HHS K01 OD010968
6 · The paper itself

Abstract

Hansen's disease (leprosy) elimination has proven difficult in several countries, including Brazil, and there is a need for a mathematical model that can predict control program efficacy. This study applied the Approximate Bayesian Computation algorithm to fit 6 different proposed models to each of the 5 regions of Brazil, then fitted hierarchical models based on the best-fit regional models to the entire country. The best model proposed for most regions was a simple model. Posterior checks found that the model results were more similar to the observed incidence after fitting than before, and that parameters varied slightly by region. Current control programs were predicted to require additional measures to eliminate Hansen's Disease as a public health problem in Brazil.

Indexed as

Mycobacterium lepraeAlgorithmsBayes TheoremBrazilCommunicable Disease ControlHumansIncidenceLeprostatic AgentsLeprosyModels, StatisticalMonte Carlo MethodProgram EvaluationLeprostatic Agents

Identifiers

PMID26107951
PMCPMC4479607

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.