Evidence map›Paper›PMID 26107818›Full record

Trial reportPloS one2015

Efficacy of Cognitive Behavioral Therapy on Opiate Use and Retention in Methadone Maintenance Treatment in China: A Randomised Trial.

Shujun Pan, Haifeng Jiang, Jiang Du, Hanhui Chen, Zhibin Li, Walter Ling, Min Zhao

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01144390 (Barriers and Effect of Optimizing Intervention Protocols for Heroin Dependence in Community-based Methadone Maintenance Treatment), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01144390 naunknown statusnot on this map

Barriers and Effect of Optimizing Intervention Protocols for Heroin Dependence in Community-based Methadone Maintenance Treatment (MMT): a Cohort Study

TypeinterventionalSponsorShanghai Mental Health CenterRan2010 to 2011Enrolled240ConditionsHeroin DependenceArmscognitive behavioral therapy, methadone maintenance treatment
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shujun PanShanghai Mental Health Center, Shanghai JiaoTong University School of Medicine, Shanghai, China, 200030.
Haifeng JiangShanghai Mental Health Center, Shanghai JiaoTong University School of Medicine, Shanghai, China, 200030.
Jiang DuShanghai Mental Health Center, Shanghai JiaoTong University School of Medicine, Shanghai, China, 200030.
Hanhui ChenShanghai Mental Health Center, Shanghai JiaoTong University School of Medicine, Shanghai, China, 200030.
Zhibin LiShanghai Mental Health Center, Shanghai JiaoTong University School of Medicine, Shanghai, China, 200030.
Walter LingIntegrated Substance Abuse Programs, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.
Min ZhaoShanghai Mental Health Center, Shanghai JiaoTong University School of Medicine, Shanghai, China, 200030.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMethadone maintenance treatment (MMT) is widely available in China; but, high rates of illicit opiate use and dropout are problematic. The aim of this study was to test whether cognitive behavioral therapy (CBT) in conjunction with MMT can improve treatment retention and reduce opiate use.

methodA total of 240 opiate-dependent patients in community-based MMT clinics were randomly assigned to either weekly CBT plus standard MMT (CBT group, n=120) or standard MMT (control group, n=120) for 26 weeks. The primary outcomes were treatment retention and opiate-negative urine test results at 12 weeks and 26 weeks. The secondary outcomes were composite scores on the Addiction Severity Index (ASI) and total scores on the Perceived Stress Scale (PSS) at 12 weeks and 26 weeks.

resultsCompared to the control group in standard MMT, the CBT group had higher proportion of opiate-negative urine tests at both 12 weeks (59% vs. 69%, p<0.05) and 26 weeks (63% vs. 73%, p<0.05); however, the retention rates at 12 weeks (73.3% vs. 74.2%, p=0.88) and 26 weeks were not different (55.8% vs. 64.2%, p=0.19) between the two groups. At both 12 and 26 weeks, all of the ASI component scores and PSS total scores in the CBT group and control group decreased from baseline; but the CBT group exhibited more decreases in ASI employment scores at week 26 and more decrease in the PSS total score at week 12 and week 26.

conclusionsCBT counselling is effective in reducing opiate use and improving employment function and in decreasing stress level for opiate-dependent patients in MMT in China.

trial registrationClinicalTrials.gov NCT01144390.

Indexed as

Cognitive Behavioral TherapyAdultChinaFemaleHeroin DependenceHumansMaleMethadoneMiddle AgedOpioid-Related DisordersPatient DropoutsTreatment OutcomeMethadone

Identifiers

PMID26107818
PMCPMC4479610

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.