Evidence map›Paper›PMID 26107117›Full record

ReviewNeuropharmacology2016

Histamine receptor signaling in energy homeostasis.

Iustin V Tabarean

Open access · greenAbstract readReview
In one paragraph

Review in Neuropharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 64 citations in OpenAlex.

  1. Trial
  2. Histamine in Diabetic Cardiovascular Complications.Reviews in cardiovascular medicine · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Histidine-Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Migraine, Allergy, and Histamine: Is There a Link?Journal of clinical medicine · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Different Peas in the Same Pod: The Histaminergic Neuronal Heterogeneity.Current topics in behavioral neurosciences · 2022
    Review
  18. Review
  19. Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19?International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Iustin V TabareanThe Department of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: tabarean@scripps.edu.
Scripps Research Institute · US

Funding

Peptidergic modulation of thermoregulation and energy expenditureR01NS094800 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI TABAREAN, IUSTIN VIRGIL · 2015 to 2019
$2.2M
Preoptic histamine signaling in thermoregulation and energy expenditureR01NS060799 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI TABAREAN, IUSTIN VIRGIL · 2009 to 2012
$1.6M
Electrophysiology of zona incerta neuronsR56NS082255 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI TABAREAN, IUSTIN VIRGIL · 2013 to 2013
$474k
NINDS NIH HHS R01 NS060799NINDS NIH HHS R01 NS094800NINDS NIH HHS R56 NS082255
6 · The paper itself

Abstract

Histamine modulates several aspects of energy homeostasis. By activating histamine receptors in the hypothalamus the bioamine influences thermoregulation, its circadian rhythm, energy expenditure and feeding. These actions are brought about by activation of different histamine receptors and/or the recruitment of distinct neural pathways. In this review we describe the signaling mechanisms activated by histamine in the hypothalamus, the evidence for its role in modulating energy homeostasis as well as recent advances in the understanding of the cellular and neural network mechanisms involved. This article is part of the Special Issue entitled 'Histamine Receptors'.

Indexed as

AnimalsBody Temperature RegulationBrainEnergy MetabolismFeeding BehaviorHistamineHomeostasisHumansReceptors, HistamineHistamineReceptors, HistamineEnergy homeostasisFeedingH1 histamine receptorH1R antagonistH2 histamine receptorH3 histamine receptorHistamineHypothalamusSignalingThermoregulation

Identifiers

PMID26107117
PMCPMC4686377
OpenAlexW823049900

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.