ReviewFrontiers in cellular and infection microbiology2015
The role of autophagy in intracellular pathogen nutrient acquisition.
Review in Frontiers in cellular and infection microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Potato purple top phytoplasma infection induces autophagy-associated lipid dynamics that support pathogen proliferation.Plant physiology · 2026Article
- Histone demethylase LSD1 regulates lipid homeostasis duringiScience · 2025Article
- Staphylococcal mastitis in dairy cows.Frontiers in veterinary science · 2024Review
- The Emerging Role of STING in Insect Innate Immune Responses and Pathogen Evasion Strategies.Frontiers in immunology · 2022Review
- Moments in autophagy and disease: Past and present.Molecular aspects of medicine · 2021Review
- Deletion ofAutophagy · 2021Article
- Article
- Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylation.Autophagy · 2020Article
- Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB.iScience · 2020Article
- Staphylococcus aureus facilitates its survival in bovine macrophages by blocking autophagic flux.Journal of cellular and molecular medicine · 2020Article
- The Host Autophagy DuringFrontiers in microbiology · 2020Review
- The role of host autophagy machinery in controllingVirulence · 2019Review
- Review
- The HIF-1α/LC3-II Axis Impacts Fungal Immunity in Human Macrophages.Infection and immunity · 2019Article
- Oncolytic paramyxoviruses-induced autophagy; a prudent weapon for cancer therapy.Journal of biomedical science · 2019Review
- Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication.Virology · 2019Article
- How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication.Frontiers in cellular and infection microbiology · 2019Review
- Bacteria Exploit Autophagy For Their Own Benefit.Infection and drug resistance · 2019Review
- Intracellular Staphylococcus aureus Modulates Host Central Carbon Metabolism To Activate Autophagy.mSphere · 2018Article
- miRNAs in Tuberculosis: New Avenues for Diagnosis and Host-Directed Therapy.Frontiers in microbiology · 2018Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following entry into host cells intracellular pathogens must simultaneously evade innate host defense mechanisms and acquire energy and anabolic substrates from the nutrient-limited intracellular environment. Most of the potential intracellular nutrient sources are stored within complex macromolecules that are not immediately accessible by intracellular pathogens. To obtain nutrients for proliferation, intracellular pathogens must compete with the host cell for newly-imported simple nutrients or degrade host nutrient storage structures into their constituent components (fatty acids, carbohydrates, and amino acids). It is becoming increasingly evident that intracellular pathogens have evolved a wide variety of strategies to accomplish this task. One recurrent microbial strategy is to exploit host degradative processes that break down host macromolecules into simple nutrients that the microbe can use. Herein we focus on how a subset of bacterial, viral, and eukaryotic pathogens leverage the host process of autophagy to acquire nutrients that support their growth within infected cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.