ArticleNeuroImage. Clinical2015
Brain structural, functional, and cognitive correlates of recent versus remote autobiographical memories in amnestic Mild Cognitive Impairment.
Article in NeuroImage. Clinical, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Tell me why: the missing w in episodic memory's what, where, and when.Cognitive, affective & behavioral neuroscience · 2025Review
- Contributions of connectional pathways to shaping Alzheimer's disease pathologies.Brain communications · 2025Article
- Brain connectivity patterns associated with individual differences in the access to experience-near personal semantics: a resting-state fMRI study.Cognitive, affective & behavioral neuroscience · 2024Article
- Mapping the long-term delayed recall-based cortex-hippocampus network constrained by the structural and functional connectome: a case-control multimodal MRI study.Alzheimer's research & therapy · 2023Article
- Associations of Neurocognition and Social Cognition With Brain Structure and Function in Early-Onset Schizophrenia.Frontiers in psychiatry · 2022Article
- Plasma Levels of Tissue-Type Plasminogen Activator (tPA) in Normal Aging and Alzheimer's Disease: Links With Cognition, Brain Structure, Brain Function and Amyloid Burden.Frontiers in aging neuroscience · 2022Article
- Quantitation of in vivo brain glutathione conformers in cingulate cortex among age-matched control, MCI, and AD patients using MEGA-PRESS.Human brain mapping · 2020Article
- Brain and cognitive correlates of sleep fragmentation in elderly subjects with and without cognitive deficits.Alzheimer's & dementia (Amsterdam, Netherlands) · 2019Article
- Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled.Current biology : CB · 2019Article
- Inter-method and anatomical correlates of episodic memory tests in the Alzheimer's Disease spectrum.PloS one · 2019Article
- Neuropsychology and neuroimaging profiles of amyloid-positive versus amyloid-negative amnestic mild cognitive impairment patients.Alzheimer's & dementia (Amsterdam, Netherlands) · 2018Article
- Voxel-based mapping of grey matter volume and glucose metabolism profiles in amyotrophic lateral sclerosis.EJNMMI research · 2017Article
- The effect of hippocampal function, volume and connectivity on posterior cingulate cortex functioning during episodic memory fMRI in mild cognitive impairment.European radiology · 2017Article
- MRI-based comparative study of different mild cognitive impairment subtypes: protocol for an observational case-control study.BMJ open · 2017Observational
- How does white matter microstructure differ between the vascular and amnestic mild cognitive impairment?Oncotarget · 2017Article
- Connectivity Disruption, Atrophy, and Hypometabolism within Posterior Cingulate Networks in Alzheimer's Disease.Frontiers in neuroscience · 2016Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deficits in autobiographical memory appear earlier for recent than for remote life periods over the course of Alzheimer's disease (AD). The present study aims to further our understanding of this graded effect by investigating the cognitive and neural substrates of recent versus remote autobiographical memories in patients with amnestic Mild Cognitive Impairment (aMCI) thanks to an autobiographical fluency task. 20 aMCI patients and 25 Healthy elderly Controls (HC) underwent neuropsychological tests assessing remote (20-to-30 years old) and recent (the ten last years) autobiographical memory as well as episodic and semantic memory, executive function and global cognition. All patients also had a structural MRI and an FDG-PET scan. Correlations were assessed between each autobiographical memory score and the other tests as well as grey matter volume and metabolism. Within the aMCI, performances for the remote period correlated with personal semantic memory and episodic memory retrieval whereas performances for the recent period only correlated with episodic memory retrieval. Neuroimaging analyses revealed significant correlations between performances for the remote period and temporal pole and temporo-parietal cortex volumes and anterior cingulate gyrus metabolism, while performances for the recent period correlated with hippocampal volume and posterior cingulate, medial prefrontal and hippocampus metabolism. The brain regions related with the retrieval of events from the recent period showed greater atrophy/hypometabolism in aMCI patients compared to HC than those involved in remote memories. Recall of recent memories essentially relies on episodic memory processes and brain network while remote memories also involve other processes such as semantic memory. This is consistent with the semanticization of memories with time and may explain the better resistance of remote memory in AD.
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