Evidence map›Paper›PMID 26106551›Full record

ArticleNeuroImage. Clinical2015

A greater involvement of posterior brain areas in interhemispheric transfer in autism: fMRI, DWI and behavioral evidences.

Elise B Barbeau, John D Lewis, Julien Doyon, Habib Benali, Thomas A Zeffiro, Laurent Mottron

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

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  9. Diffusion Tensor Imaging Shows Corpus Callosum Differences between High-Grade Gliomas and Metastases.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Elise B BarbeauCentre d'Excellence en Troubles Envahissants du Développement de l'Université de Montréal (CETEDUM), Montréal, QC, Canada ; Centre de recherche de l'Institut universitaire de santé mentale de Montréal, Montréal, QC, Canada ; Département de Psychiatrie, Université de Montréal, Montréal, QC, Canada.
John D LewisMontreal Neurological Institute, McGill University, Montréal, QC, Canada.
Julien DoyonDépartement de Psychologie de l'Université de Montréal & Unité de Neuroimagerie Fonctionnelle (UNF), Montréal, QC, Canada.
Habib BenaliLaboratoire d'Imagerie Fonctionnelle - U678, Faculté de Médecine Pierre et Marie Curie - Pitié Salpétrière, Paris, France.
Thomas A ZeffiroNeural Systems Group, Massachusetts General Hospital, Psychiatry, Charlestown, MA, USA.
Laurent MottronCentre d'Excellence en Troubles Envahissants du Développement de l'Université de Montréal (CETEDUM), Montréal, QC, Canada ; Centre de recherche de l'Institut universitaire de santé mentale de Montréal, Montréal, QC, Canada ; Département de Psychiatrie, Université de Montréal, Montréal, QC, Canada.
Université de Montréal · CAMassachusetts General Hospital · USMontreal Neurological Institute and Hospital · CASorbonne Université · FR

Funding

Canadian Institutes of Health Research MOP-84243
6 · The paper itself

Abstract

A small corpus callosum (CC) is one of the most replicated neurobiological findings in autism spectrum (AS). However, its effect on interhemispheric (IH) communication is unknown. We combined structural (CC area and DWI), functional (task-related fMRI activation and connectivity analyses) as well as behavioral (Poffenberger and Purdue tasks) measures to investigate IH integration in adult AS individuals of typical intelligence. Despite similar behavioral IH transfer time and performances in bimanual tasks, the CC sub-regions connecting frontal and parietal cortical areas were smaller in AS than in non-AS individuals, while those connecting visual regions were similar. The activation of visual areas was lower in AS than in non-AS individuals during the presentation of visual stimuli. Behavioral IH performances were related to the properties of CC subregions connecting motor areas in non-AS individuals, but to the properties of posterior CC regions in AS individuals. Furthermore, there was greater functional connectivity between visual areas in the AS than in the non-AS group. Levels of connectivity were also stronger in visual than in motor regions in the autistic subjects, while the opposite was true for the non-autistic group. Thus, visual IH transfer plays an important role in visuo-motor tasks in AS individuals. These findings extend the well established enhanced role of perception in autistic cognition to visuo-motor IH information transfer.

Indexed as

AdolescentAdultAutism Spectrum DisorderCerebral CortexCorpus CallosumDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingMalePsychomotor PerformanceYoung AdultAutismCorpus callosumCortical reorganizationPoffenbergerPurdueVisuo-motor integration

Identifiers

PMID26106551
PMCPMC4474173
OpenAlexW2036127308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.