Evidence map›Paper›PMID 26106401›Full record

ReviewFrontiers in plant science2015

Closing the loop on the GABA shunt in plants: are GABA metabolism and signaling entwined?

Simon Michaeli, Hillel Fromm

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
32.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 309 citations in OpenAlex.

  1. Review
  2. Article
  3. TaGAD2 is a potential downstream effector of Rht5 in controlling wheat plant height.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  6. Review
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  11. Review
  12. Article
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  15. Article
  16. Article
  17. Patch-Clamp- andPlant, cell & environment · 2025
    Article
  18. Article
  19. Metabolite Profiling of the Resurrection GrassPlants (Basel, Switzerland) · 2025
    Article
  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Simon MichaeliDepartment of Molecular Biology and Ecology of Plants, Faculty of Life Sciences, Tel Aviv University , Tel Aviv, Israel.
Hillel FrommDepartment of Molecular Biology and Ecology of Plants, Faculty of Life Sciences, Tel Aviv University , Tel Aviv, Israel.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

γ-Aminobutyric acid (GABA) is a non-proteinogenic amino acid that is found in uni- and multi-cellular organisms and is involved in many aspects of plant life cycle. GABA metabolism occurs by the action of evolutionary conserved enzymes that constitute the GABA shunt, bypassing two steps of the TCA cycle. The central position of GABA in the interface between plant carbon and nitrogen metabolism is well established. In parallel, there is evidence to support a role for GABA as a signaling molecule in plants. Here we cover some of the recent findings on GABA metabolism and signaling in plants and further suggest that the metabolic and signaling aspects of GABA may actually be inseparable.

Indexed as

ArabidopsisGABA shuntglutamate decarboxylasestresstricarboxylic acidsγ-Aminobutyric acid

Identifiers

PMID26106401
PMCPMC4460296
OpenAlexW1597389584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.