ArticleThe Plant cell2015
Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes.
Article in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- An extragenic second-site mutation in the jar1-1 mutant suppresses the response to photoperiod stress independent of jasmonic acid.Plant molecular biology · 2025Article
- Discovery of a second-site nia2 mutation in the background of multiple Arabidopsis PIF-related mutants containing the pif3-3 allele.The New phytologist · 2024Article
- Article
- Is it the end of TILLING era in plant science?Frontiers in plant science · 2023Review
- Short-interval traffic lines: versatile tools for genetic analysis in Arabidopsis thaliana.G3 (Bethesda, Md.) · 2022Article
- The Story of Auxin-Binding Protein 1 (ABP1).Cold Spring Harbor perspectives in biology · 2021Review
- Interdependence of a mechanosensitive anion channel and glutamate receptors in distal wound signaling.Science advances · 2021Article
- Article
- Function of membrane domains in rho-of-plant signaling.Plant physiology · 2021Review
- Auxin does not inhibit endocytosis of PIN1 and PIN2 auxin efflux carriers.Plant physiology · 2021Article
- Exogenous Auxin Induces Transverse Microtubule Arrays Through TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX Receptors.Plant physiology · 2020Article
- The root hair defective phenotype ofmicroPublication biology · 2019Article
- Auxin Signaling.Plant physiology · 2018Review
- Protoplast Swelling and Hypocotyl Growth Depend on Different Auxin Signaling Pathways.Plant physiology · 2017Article
- Effects of Auxins on PIN-FORMED2 (PIN2) Dynamics Are Not Mediated by Inhibiting PIN2 Endocytosis.Plant physiology · 2016Article
- Auxin perception and downstream events.Current opinion in plant biology · 2016Review
- Differential Regulation of Clathrin and Its Adaptor Proteins during Membrane Recruitment for Endocytosis.Plant physiology · 2016Article
- A Proposal Regarding Best Practices for Validating the Identity of Genetic Stocks and the Effects of Genetic Variants.The Plant cell · 2016Article
- Ws-2 Introgression in a Proportion of Arabidopsis thaliana Col-0 Stock Seed Produces Specific Phenotypes and Highlights the Importance of Routine Genetic Verification.The Plant cell · 2016Article
- Regulation of developmental and environmental signaling by interaction between microtubules and membranes in plant cells.Protein & cell · 2016Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Auxin regulates numerous aspects of plant growth and development. For many years, investigating roles for AUXIN BINDING PROTEIN1 (ABP1) in auxin response was impeded by the reported embryo lethality of mutants defective in ABP1. However, identification of a viable Arabidopsis thaliana TILLING mutant defective in the ABP1 auxin binding pocket (abp1-5) allowed inroads into understanding ABP1 function. During our own studies with abp1-5, we observed growth phenotypes segregating independently of the ABP1 lesion, leading us to sequence the genome of the abp1-5 line described previously. We found that the abp1-5 line we sequenced contains over 8000 single nucleotide polymorphisms in addition to the ABP1 mutation and that at least some of these mutations may originate from the Arabidopsis Wassilewskija accession. Furthermore, a phyB null allele in the abp1-5 background is likely causative for the long hypocotyl phenotype previously attributed to disrupted ABP1 function. Our findings complicate the interpretation of abp1-5 phenotypes for which no complementation test was conducted. Our findings on abp1-5 also provide a cautionary tale illustrating the need to use multiple alleles or complementation lines when attributing roles to a gene product.
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