ArticleBMC plant biology2015
The ARGOS gene family functions in a negative feedback loop to desensitize plants to ethylene.
Article in BMC plant biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 64 citations in OpenAlex.
- Rorippa islandica: a genetically accessible dicot model system to study flooding tolerance.Plant physiology · 2026Article
- A review of ARGOS-mediated regulation of plant organ size: molecular mechanisms, environmental interactions, and agricultural implications.Functional & integrative genomics · 2026Review
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- ARGOS homolog evolution in brassicaceae and the role of BnaC6.ARGOS in conferring drought tolerance via expression-responsive localization and reduced seed porosity in rapeseed.BMC plant biology · 2025Article
- Genetic diversity and adaptive evolutionary history of Sapindus in China: insights from whole-genome resequencing of 100 representative individuals.Plant biotechnology journal · 2025Article
- Diverse roles of ethylene in maize growth and development, and its importance in shaping plant architecture.Journal of experimental botany · 2025Review
- Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought.Plants (Basel, Switzerland) · 2025Review
- Membrane protein MHZ3 regulates the on-off switch of ethylene signaling in rice.Nature communications · 2024Article
- Have All of the Phytohormonal Properties of Melatonin Been Verified?International journal of molecular sciences · 2024Review
- LTP2 hypomorphs show genotype-by-environment interaction in early seedling traits in Arabidopsis thaliana.The New phytologist · 2024Article
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- Basis for high-affinity ethylene binding by the ethylene receptor ETR1 of Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The retrograde signaling regulator ANAC017 recruits the MKK9-MPK3/6, ethylene, and auxin signaling pathways to balance mitochondrial dysfunction with growth.The Plant cell · 2022Article
- Expression profiling of TaARGOS homoeologous drought responsive genes in bread wheat.Scientific reports · 2022Article
- Atypical Climacteric and Functional Ethylene Metabolism and Signaling During Fruit Ripening in Blueberry (Frontiers in plant science · 2022Article
- Comparative transcriptome analysis revealed differential gene expression in multiple signaling pathways at flowering in polyploid Brassica rapa.Cell & bioscience · 2021Article
- Ethylene signaling in plants.The Journal of biological chemistry · 2020Review
- Analysis of the impact of indole-3-acetic acid (IAA) on gene expression during leaf senescence inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Role of the Cytokinin-Activated Type-B Response Regulators in Hormone Crosstalk.Plants (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEthylene plays critical roles in plant growth and development, including the regulation of cell expansion, senescence, and the response to biotic and abiotic stresses. Elements of the initial signal transduction pathway have been determined, but we are still defining regulatory mechanisms by which the sensitivity of plants to ethylene is modulated.
resultsWe report here that members of the ARGOS gene family of Arabidopsis, previously implicated in the regulation of plant growth and biomass, function as negative feedback regulators of ethylene signaling. Expression of all four members of the ARGOS family is induced by ethylene, but this induction is blocked in ethylene-insensitive mutants. The dose dependence for ethylene induction varies among the ARGOS family members, suggesting that they could modulate responses across a range of ethylene concentrations. GFP-fusions of ARGOS and ARL localize to the endoplasmic reticulum, the same subcellular location as the ethylene receptors and other initial components of the ethylene signaling pathway. Seedlings with increased expression of ARGOS family members exhibit reduced ethylene sensitivity based on physiological and molecular responses.
conclusionsThese results support a model in which the ARGOS gene family functions as part of a negative feedback circuit to desensitize the plant to ethylene, thereby expanding the range of ethylene concentrations to which the plant can respond. These results also indicate that the effects of the ARGOS gene family on plant growth and biomass are mediated through effects on ethylene signal transduction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.