ArticlePlanta2015
Biochemical characterization of allene oxide synthases from the liverwort Marchantia polymorpha and green microalgae Klebsormidium flaccidum provides insight into the evolutionary divergence of the plant CYP74 family.
Article in Planta, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 57 citations in OpenAlex.
- Jasmonate Biosynthesis Across Bryophyte Lineages: Lessons fromPlants (Basel, Switzerland) · 2026Review
- Cytochromes P450 evolution in the plant terrestrialization context.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Phytohormone profiling in an evolutionary framework.Nature communications · 2024Article
- Allene oxide synthase 1 contributes to limiting grain arsenic accumulation and seedling detoxification in rice.Stress biology · 2023Article
- Ketols Emerge as Potent Oxylipin Signals Regulating Diverse Physiological Processes in Plants.Plants (Basel, Switzerland) · 2023Review
- CRISPR/Cas9-mediated disruption ofPlant biotechnology (Tokyo, Japan) · 2022Article
- Cytochrome P450s in algae: Bioactive natural product biosynthesis and light-driven bioproduction.Acta pharmaceutica Sinica. B · 2022Review
- A non-targeted metabolomics analysis identifies wound-induced oxylipins inFrontiers in plant science · 2022Article
- Detection of the First Epoxyalcohol Synthase/Allene Oxide Synthase (CYP74 Clan) in the Lancelet (International journal of molecular sciences · 2021Article
- Green Leaf Volatile-Burst inFrontiers in plant science · 2021Article
- Molecular Interaction and Evolution of Jasmonate Signaling With Transport and Detoxification of Heavy Metals and Metalloids in Plants.Frontiers in plant science · 2021Review
- Jasmonate-Related MYC Transcription Factors Are Functionally Conserved inThe Plant cell · 2019Article
- Membrane Lipids, Waxes and Oxylipins in the Moss Model Organism Physcomitrella patens.Plant & cell physiology · 2019Review
- The CYP443C1 (CYP74 clan) Cytochrome of Sea Anemone Nematostella vectensis-the First Metazoan Enzyme Possessing Hydroperoxide Lyase/Epoxyalcohol Synthase Activity.Doklady. Biochemistry and biophysics · 2019Article
- Jasmonates: News on Occurrence, Biosynthesis, Metabolism and Action of an Ancient Group of Signaling Compounds.International journal of molecular sciences · 2018Review
- Silkworms suppress the release of green leaf volatiles by mulberry leaves with an enzyme from their spinnerets.Scientific reports · 2018Article
- Ligand-receptor co-evolution shaped the jasmonate pathway in land plants.Nature chemical biology · 2018Article
- On plant defense signaling networks and early land plant evolution.Communicative & integrative biology · 2018Review
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MAIN
conclusionAllene oxide synthases (AOSs) were isolated from liverworts and charophytes. These AOSs exhibited enzymatic properties similar to those of angiosperms but formed a distinct phylogenetic clade. Allene oxide synthase (AOS) and hydroperoxide lyase (HPL) mediate the formation of precursors of jasmonates and carbon-six volatiles, respectively. AOS and HPL utilize fatty acid hydroperoxides and belong to the plant cytochrome P450 74 (CYP74) family that mediates plant defense against herbivores, pathogens, or abiotic stresses. Although members of the CYP74 family have been reported in mosses and other species, the evolution and function of multiple CYP74 genes in plants remain elusive. Here, we show that the liverwort Marchantia polymorpha belongs to a basal group in the evolution of land plants; has two closely related proteins (59% identity), MpAOS1 and MpAOS2, that are similar to moss PpAOS1 (49 and 47% identity, respectively); and exhibits AOS activity but not HPL activity. We also found that the green microalgae Klebsormidium flaccidum, consist of multicellular and non-branching filaments, contains an enzyme, KfAOS, that is similar to PpAOS1 (37% identity), and converts 13-hydroperoxide of linolenic acid to 12-oxo-phytodienoic acid in a coupled reaction with allene oxide cyclase. Phylogenetic analysis showed two evolutionarily distinct clusters. One cluster comprised AOS and HPL from charophytic algae, liverworts, and mosses, including MpAOSs and KfAOS. The other cluster was formed by angiosperm CYP74. Our results suggest that plant CYP74 enzymes with AOS, HPL, and divinyl ether synthase activities have arisen multiple times and in the two different clades, which occurred prior to the divergence of the flowering plant lineage.
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