ArticleEuropean journal of nuclear medicine and molecular imaging2015
Multi-contrast attenuation map synthesis for PET/MR scanners: assessment on FDG and Florbetapir PET tracers.
Article in European journal of nuclear medicine and molecular imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 41 citations in OpenAlex.
- Image harmonization improves consistency of intra-rater delineations of MS lesions in heterogeneous MRI.Neuroimage. Reports · 2024Article
- A review of PET attenuation correction methods for PET-MR.EJNMMI physics · 2023Review
- Evaluation of three methods for delineation and attenuation estimation of the sinus region in MR-based attenuation correction for brain PET-MR imaging.BMC medical imaging · 2022Article
- Article
- Accuracy and precision of zero-echo-time, single- and multi-atlas attenuation correction for dynamic [EJNMMI physics · 2020Article
- Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020Article
- Amyloid β influences the relationship between cortical thickness and vascular load.Alzheimer's & dementia (Amsterdam, Netherlands) · 2020Article
- Zero Echo Time MRAC on FDG-PET/MR Maintains Diagnostic Accuracy for Alzheimer's Disease; A Simulation Study Combining ADNI-Data.Frontiers in neuroscience · 2020Article
- Article
- Impact of Tissue Classification in MRI-Guided Attenuation Correction on Whole-Body Patlak PET/MRI.Molecular imaging and biology · 2019Article
- Reduced acquisition time PET pharmacokinetic modelling using simultaneous ASL-MRI: proof of concept.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- Hippocampal subfield volumes and pre-clinical Alzheimer's disease in 408 cognitively normal adults born in 1946.PloS one · 2019Article
- Evaluation of zero-echo-time attenuation correction for integrated PET/MR brain imaging-comparison to head atlas andEJNMMI physics · 2018Article
- NiftyPET: a High-throughput Software Platform for High Quantitative Accuracy and Precision PET Imaging and Analysis.Neuroinformatics · 2018Article
- EANM/EARL harmonization strategies in PET quantification: from daily practice to multicentre oncological studies.European journal of nuclear medicine and molecular imaging · 2017Review
- Iterative framework for the joint segmentation and CT synthesis of MR images: application to MRI-only radiotherapy treatment planning.Physics in medicine and biology · 2017Article
- Evaluation of a multi-atlas CT synthesis approach for MRI-only radiotherapy treatment planning.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2017Article
- Clinical PET/MRI in neurooncology: opportunities and challenges from a single-institution perspective.Clinical and translational imaging · 2017Review
- Reconstruction of 7T-Like Images From 3T MRI.IEEE transactions on medical imaging · 2016Article
- Using florbetapir positron emission tomography to explore cerebrospinal fluid cut points and gray zones in small sample sizes.Alzheimer's & dementia (Amsterdam, Netherlands) · 2015Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Positron Emission Tomography/Magnetic Resonance Imaging (PET/MR) scanners are expected to offer a new range of clinical applications. Attenuation correction is an essential requirement for quantification of PET data but MRI images do not directly provide a patient-specific attenuation map. Methods We further validate and extend a Computed Tomography (CT) and attenuation map (μ-map) synthesis method based on pre-acquired MRI-CT image pairs. The validation consists of comparing the CT images synthesised with the proposed method to the original CT images. PET images were acquired using two different tracers ((18)F-FDG and (18)F-florbetapir). They were then reconstructed and corrected for attenuation using the synthetic μ-maps and compared to the reference PET images corrected with the CT-based μ-maps. During the validation, we observed that the CT synthesis was inaccurate in areas such as the neck and the cerebellum, and propose a refinement to mitigate these problems, as well as an extension of the method to multi-contrast MRI data. Results With the improvements proposed, a significant enhancement in CT synthesis, which results in a reduced absolute error and a decrease in the bias when reconstructing PET images, was observed. For both tracers, on average, the absolute difference between the reference PET images and the PET images corrected with the proposed method was less than 2%, with a bias inferior to 1%. Conclusion With the proposed method, attenuation information can be accurately derived from MRI images by synthesising CT using routine anatomical sequences. MRI sequences, or combination of sequences, can be used to synthesise CT images, as long as they provide sufficient anatomical information.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.