Evidence map›Paper›PMID 26105036›Full record

ArticleHeart (British Cardiac Society)2015

Acute and recent air pollution exposure and cardiovascular events at labour and delivery.

Tuija Männistö, Pauline Mendola, Katherine Laughon Grantz, Kira Leishear, Rajeshwari Sundaram, Seth Sherman, Qi Ying, Danping Liu

Abstract read
In one paragraph

Article in Heart (British Cardiac Society), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
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  15. Gaseous Air Pollution and the Risk for Stroke Admissions: A Case-Crossover Study in Beijing, China.International journal of environmental research and public health · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tuija MännistöEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA Northern Finland Laboratory Centre NordLab, Oulu, Finland Department of Clinical Chemistry, University of Oulu, Oulu, Finland Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland Department of Chronic Disease Prevention, National Institute for Health and Welfare, Oulu, Finland.
Pauline MendolaEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA.
Katherine Laughon GrantzEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA.
Kira LeishearGlotech Inc., Rockville, Maryland, USA US Food and Drug Administration, Silver Spring, Maryland, USA.
Rajeshwari SundaramBiostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA.
Seth ShermanThe EMMES Corporation, Rockville, Maryland, USA.
Qi YingZachry Department of Civil Engineering, Texas A&M University, College Station, Texas, USA.
Danping LiuBiostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA.

Funding

Consortium on Safe LaborZIAHD008794 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GRANTZ, KATHERINE · 2009 to 2022
$3.2M
Air Quality and Reproductive HealthZIAHD008923 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MENDOLA, PAULINE · 2012 to 2020
$3.2M
Statistical methods in analyzing complex longitudinal dataZIAHD008953 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI LIU, DANPING · 2015 to 2017
$915k
Intramural NIH HHS ZIA HD008794Intramural NIH HHS ZIA HD008923NICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002I
6 · The paper itself

Abstract

objectiveTo study the relationship between acute air pollution exposure and cardiovascular events during labour/delivery.

methodsThe Consortium on Safe Labor (2002-2008), an observational US cohort with 223,502 singleton deliveries provided electronic medical records. Air pollution exposure was estimated by modified Community Multiscale Air Quality models. Cardiovascular events (cardiac failure/arrest, stroke, myocardial infarcts and other events) were recorded in the hospital discharge records for 687 pregnancies (0.3%). Logistic regression with generalised estimating equations estimated the relationship between cardiovascular events and daily air pollutant levels for delivery day and the 7 days preceding delivery.

resultsIncreased odds of cardiovascular events were observed for each IQR increase in exposure to nitric oxides at 5 and 6 days prior to delivery (OR=1.17, 99% CI 1.04 to 1.30 and OR=1.15, 1.03 to 1.28, respectively). High exposure to toxic air pollution species such as ethylbenzene (OR=1.50, 1.08 to 2.09), m-xylene (OR=1.54, 1.11 to 2.13), o-xylene (OR=1.51, 1.09 to 2.09), p-xylene (OR=1.43, 1.03 to 1.99) and toluene (OR=1.42, 1.02 to 1.97) at 5 days prior to delivery were also associated with cardiovascular events. Decreased odds of events were observed with exposure to ozone.

conclusionsAir pollution in the days prior to delivery, especially nitrogen oxides and some toxic air pollution species, was associated with increased risk of cardiovascular events during the labour/delivery admission.

Indexed as

Air PollutionEnvironmental ExposureNitrogen OxidesOzonePregnancy Complications, CardiovascularXylenesAdultDelivery, ObstetricElectronic Health RecordsFemaleHumansMaleOutcome Assessment, Health CarePregnancyRisk AssessmentRisk FactorsNitrogen OxidesOzoneXylenes

Identifiers

PMID26105036
PMCPMC5575746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.