Evidence map›Paper›PMID 26104784›Full record

ArticleBMC health services research2015

Productivity loss and indirect costs associated with cardiovascular events and related clinical procedures.

Xue Song, Ruben G W Quek, Shravanthi R Gandra, Katherine A Cappell, Robert Fowler, Ze Cong

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. The Impact of Cardiovascular Disease on Economic Loss.Arquivos brasileiros de cardiologia · 2024
    Article
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  9. Article
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  14. Average lost work productivity due to non-fatal injuries by type in the USA.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xue SongTruven Health Analytics, Ann Arbor, MI, USA. xue.song@truvenhealth.com.
Ruben G W QuekAmgen, Thousand Oaks, CA, USA. rquek@amgen.com.
Shravanthi R GandraAmgen, Thousand Oaks, CA, USA. sgandra@amgen.com.
Katherine A CappellTruven Health Analytics, Ann Arbor, MI, USA. katherine.cappell@truvenhealth.com.
Robert FowlerTruven Health Analytics, Ann Arbor, MI, USA. rob.fowler@truvenhealth.com.
Ze CongOnyx Pharmaceuticals, Inc., South San Francisco, CA, USA. zcong@amgen.com.
Truven Health Analytics (United States) · USAmgen (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe high acute costs of cardiovascular disease and acute cardiovascular events are well established, particularly in terms of direct medical costs. The costs associated with lost work productivity have been described in a broad sense, but little is known about workplace absenteeism or short term disability costs among high cardiovascular risk patients. The objective of this study was to quantify workplace absenteeism (WA) and short-term disability (STD) hours and costs associated with cardiovascular events and related clinical procedures (CVERP) in United States employees with high cardiovascular risk.

methodsMedical, WA and/or STD data from the Truven Health MarketScan® Research Databases were used to select full-time employees aged 18-64 with hyperlipidemia during 2002-2011. Two cohorts (with and without CVERP) were created and screened for medical, drug, WA, and STD eligibility. The CVERP cohort was matched with a non-CVERP cohort using propensity score matching. Work loss hours and indirect costs were calculated for patients with and without CVERP and by CVERP type. Wages were based on the 2013 age-, gender-, and geographic region-adjusted wage rate from the United States Bureau of Labor Statistics.

resultsA total of 5,808 WA-eligible, 21,006 STD-eligible, and 3,362 combined WA and STD eligible patients with CVERP were well matched to patients without CVERP, creating three cohorts of patients with CVERP and three cohorts of patients without CVERP. Demographics were similar across cohorts (mean age 52.2-53.1 years, male 81.3-86.8%). During the first month of follow-up, patients with CVERP had more WA/STD-related hours lost compared with patients without CVERP (WA-eligible: 23.4 more hours, STD-eligible: 51.7 more hours, WA and STD-eligible: 56.3 more hours) (p < 0.001). Corresponding costs were $683, $895, and $1,119 higher, respectively (p < 0.001). Differences narrowed with longer follow-up. In the first month and year of follow-up, patients with coronary artery bypass graft experienced the highest WA/STD-related hours lost and costs compared with patients with other CVERP.

conclusionsCVERP were associated with substantial work loss and indirect costs. Prevention or reduction of CVERP could result in WA and STD-related cost savings for employers.

Indexed as

AbsenteeismCost of IllnessEfficiencyAdolescentAdultCardiovascular DiseasesDatabases, FactualEmploymentFemaleHumansMaleMiddle AgedPersons with DisabilitiesPropensity ScoreRisk FactorsUnited States

Identifiers

PMID26104784
PMCPMC4478719
OpenAlexW1587509141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.