Evidence map›Paper›PMID 26104084›Full record

ArticleLeukemia & lymphoma2016

Genetics of anaplastic large cell lymphoma.

Yu Zeng, Andrew L Feldman

Abstract read
In one paragraph

Article in Leukemia & lymphoma, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  11. Genomics of LGL leukemia and select other rare leukemia/lymphomas.Best practice & research. Clinical haematology · 2019
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yu Zenga Department of Laboratory Medicine and Pathology , Mayo Clinic , Rochester , MN , USA.
Andrew L Feldmana Department of Laboratory Medicine and Pathology , Mayo Clinic , Rochester , MN , USA.

Funding

Genetic Biomarkers for Risk Assessment of Peripheral T-Cell LymphomasR01CA177734 · NCI · MAYO CLINIC ROCHESTER · PI FELDMAN, ANDREW LEWIS · 2013 to 2017
$1.6M
NCI NIH HHS R01 CA177734
6 · The paper itself

Abstract

Anaplastic large cell lymphoma (ALCL) comprises a group of T-cell non-Hodgkin lymphomas unified by common morphologic and immunophenotypic characteristics, but with a spectrum of clinical presentations and behaviors. Early identification of anaplastic lymphoma kinase (ALK) gene rearrangements in some ALCLs led to recognition of ALK as an important diagnostic and prognostic biomarker, and a key driver of ALCL pathobiology. Rearrangements and other genetic abnormalities of ALK subsequently were identified in diverse other human malignancies. Recent clinical, pathologic, and genetic data have begun to shed light on ALK-negative ALCLs, revealing significant heterogeneity within this more ill-defined entity.

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseAnaplastic Lymphoma KinaseChromosome AberrationsDNA Copy Number VariationsGene Expression ProfilingGene RearrangementHumansLymphoma, Large-Cell, AnaplasticMicroRNAsReceptor Protein-Tyrosine KinasesTranscriptomeALK protein, humanAnaplastic Lymphoma KinaseMicroRNAsReceptor Protein-Tyrosine KinasesAnaplastic large cell lymphomaanaplastic lymphoma kinase (ALK)DUSP22geneticsp63T-cell non-Hodgkin lymphoma

Identifiers

PMID26104084
PMCPMC4732699

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.