Evidence map›Paper›PMID 26103977›Full record

ReviewMicrobiology spectrum2014

Metallobiology of Tuberculosis.

G Marcela Rodriguez, Olivier Neyrolles

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The role of transcriptional regulators in metal ion homeostasis ofFrontiers in cellular and infection microbiology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C.Protein science : a publication of the Protein Society · 2021
    Article
  10. Review
  11. Exposure ofAntibiotics (Basel, Switzerland) · 2020
    Article
  12. Article
  13. Review
  14. Iron Regulation in Elderly Asian Elephants (Frontiers in veterinary science · 2020
    Article
  15. Article
  16. Microbiology spectrum · 2019
    Review
  17. The Capacity ofmBio · 2017
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

G Marcela RodriguezPublic Health Research Institute and New Jersey Medical School-Rutgers, the State University of New Jersey, Newark, NJ 07103.
Olivier NeyrollesCentre National de la Recherche Scientifique and Université de Toulouse, Université Paul Sabatier, Institut de Pharmacologie et de Biologie Structurale, Toulouse, France.
Rutgers, The State University of New Jersey · USUniversité Toulouse III - Paul Sabatier · FR

Funding

M TUBERCULOSIS SURVIVAL AND GROWTH IN VIVOR01AI044856 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI RODRIGUEZ, GLORIA MARCELA, SMITH, ISSAR · 1999 to 2014
$6.8M
Mechanisms and regulation of Mycobacterium tuberculosis iron acquisitionR56AI044856 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI RODRIGUEZ, GLORIA MARCELA, SMITH, ISSAR · 2009 to 2009
$585k
NIAID NIH HHS AI44856NIAID NIH HHS R01 AI044856NIAID NIH HHS R56 AI044856
6 · The paper itself

Abstract

Transition metals are essential constituents of all living organisms, playing crucial structural and catalytic parts in many enzymes and transcription factors. However, transition metals can also be toxic when present in excess. Their uptake and efflux rates must therefore be carefully controlled by biological systems. In this chapter, we summarize the current knowledge about uptake and efflux systems in Mycobacterium tuberculosis for mainly three of these metals, namely iron, zinc, and copper. We also propose questions for future research in the field of metallobiology of host-pathogen interactions in tuberculosis.

Indexed as

HomeostasisHumansMembrane Transport ProteinsMetalsMycobacterium tuberculosisTransition ElementsTuberculosisMembrane Transport ProteinsMetalsTransition Elements

Identifiers

PMID26103977
PMCPMC5180607
OpenAlexW2042627065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.