ArticleScientific reports2015
Towards combinatorial mixing devices without any pumps by open-capillary channels: fundamentals and applications.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Real-time observation of the precursor film for low viscosity liquids spreading on solid substrates by a customized differential laser interference microscopy.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023Article
- Spontaneous Transport Mechanics of Water Droplets under a Synergistic Action of Designed Pattern and Non-Wetting Gradient.ACS omega · 2023Article
- Evaporative and Wicking Functionalities at Hot Airflows of Laser Nano-/Microstructured Ti-6Al-4V Material.Nanomaterials (Basel, Switzerland) · 2023Article
- Characterization of Fluidic-Barrier-Based Particle Generation in Centrifugal Microfluidics.Micromachines · 2022Article
- Silicone Nanofilament Support Layers in an Open-Channel System for the Fast Reduction ofNanomaterials (Basel, Switzerland) · 2021Article
- Geometry-induced capillary emptying.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- 3D printed auto-mixing chip enables rapid smartphone diagnosis of anemia.Biomicrofluidics · 2016Article
- Scaling crossover in thin-film drag dynamics of fluid drops in the Hele-Shaw cell.Scientific reports · 2016Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In chemistry, biology, medical sciences and pharmaceutical industries, many reactions have to be checked by transporting and mixing expensive liquids. For such purposes, microfluidics systems consisting of closed channels with external pumps have been useful. However, the usage has been limited because of high fabrication cost and need for a fixed setup. Here, we show that open-capillary channels, which can be fabricated outside a clean room on durable substrates and are washable and reusable, are considerably promising for micro-devices that function without pumps, as a result of detailed studies on the imbibition of open micro-channels. We find that the statics and dynamics of the imbibition follow simple scaling laws in a wide and practical range; although a precursor film obeying a universal dynamics appears in the vertical imbibition, it disappears in the horizontal mode to make the design of complex micro-channel geometry feasible. We fabricate micro open-channel devices without any pumps to express the green fluorescent protein (GFP) by transporting highly viscous solutions and to accomplish simultaneous chemical reactions for the Bromothymol blue (BTB) solution. We envision that open-capillary devices will become a simple and low-cost option to achieve microfluidic devices that are usable in small clinics and field studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.