Evidence map›Paper›PMID 26102599›Full record

ArticleDevelopmental cell2015

Translating Membrane Tension into Cytoskeletal Action by FBP17.

Mirjam M Zegers, Peter Friedl

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mirjam M ZegersDepartment of Cell Biology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands. Electronic address: mirjam.zegers@radboudumc.nl.
Peter FriedlDepartment of Cell Biology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; David H. Koch Center for Applied Research of Genitourinary Cancers, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA; Cancer Genomics Centre Netherlands (CGC.nl), 3584 CG Utrecht, the Netherlands. Electronic address: peter.friedl@radboudumc.nl.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
6 · The paper itself

Abstract

A recent article by Tsujita et al. (2015) in Nature Cell Biology provides insight into how cells sense and translate plasma membrane tension toward polarized actin polymerization and migration. They identify FBP17 as a multifunctional adaptor that senses membrane curvature and delivers feedback to actin dynamics and directed cell migration.

Indexed as

ActinsAnimalsCarrier ProteinsCell MembraneCell MovementCell PolarityHumansActinsCarrier Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.