Evidence map›Paper›PMID 26102488›Full record

ReviewSensors (Basel, Switzerland)2015

DNA-Based Nanobiosensors as an Emerging Platform for Detection of Disease.

Khalid M Abu-Salah, Mohammed M Zourob, Fouzi Mouffouk, Salman A Alrokayan, Manal A Alaamery, Anees A Ansari

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Application of biosensors in cancers, an overview.Frontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khalid M Abu-SalahResearch Chair for Medical Applications of Nanomaterials, King Saud University, PO Box 2454, Riyadh 11451, Saudi Arabia. k_abusalah@hotmail.com.
Mohammed M ZourobDepartment of Chemistry, Alfaisal University, Al Zahrawi Street, Al Maather, Al Takhassusi Rd, Riyadh 11533, Saudi Arabia. mzourob@alfaisal.edu.
Fouzi MouffoukChemistry Department, Faculty of Science, Kuwait University, PO Box 2969, Kuwait. fmouffouk@ku.edu.kw.
Salman A AlrokayanResearch Chair for Medical Applications of Nanomaterials, King Saud University, PO Box 2454, Riyadh 11451, Saudi Arabia. aneesaansari@gmail.com.
Manal A AlaameryKing Abdulla International Medical Research Center, King Abdulaziz Medical City, PO Box 22490, Riyadh 11426, Saudi Arabia. alaameryma@ngha.med.sa.
Anees A AnsariKing Abdullah Institute for Nanotechnology, King Saud University, PO Box 2454, Riyadh 11451, Saudi Arabia. aneesaansari@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection of disease at an early stage is one of the biggest challenges in medicine. Different disciplines of science are working together in this regard. The goal of nanodiagnostics is to provide more accurate tools for earlier diagnosis, to reduce cost and to simplify healthcare delivery of effective and personalized medicine, especially with regard to chronic diseases (e.g., diabetes and cardiovascular diseases) that have high healthcare costs. Up-to-date results suggest that DNA-based nanobiosensors could be used effectively to provide simple, fast, cost-effective, sensitive and specific detection of some genetic, cancer, and infectious diseases. In addition, they could potentially be used as a platform to detect immunodeficiency, and neurological and other diseases. This review examines different types of DNA-based nanobiosensors, the basic principles upon which they are based and their advantages and potential in diagnosis of acute and chronic diseases. We discuss recent trends and applications of new strategies for DNA-based nanobiosensors, and emphasize the challenges in translating basic research to the clinical laboratory.

Indexed as

Biosensing TechniquesMolecular Diagnostic TechniquesPrecision MedicineDNAHumansDNAcancerDNA nanobiosensorselectrochemical and optical sensinggenetic and infectious diseasesnanoparticles

Identifiers

PMID26102488
PMCPMC4507582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.