Evidence map›Paper›PMID 26102308›Full record

ArticleAJR. American journal of roentgenology2015

Vascular Imaging With Ferumoxytol as a Contrast Agent.

Michael D Hope, Thomas A Hope, Chengcheng Zhu, Farshid Faraji, Henrik Haraldsson, Karen G Ordovas, David Saloner

Registry-linked trialAbstract read
In one paragraph

Article in AJR. American journal of roentgenology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06551805 (Clinical Research Protocol of Ferumoxytol for Magnetic Resonance Enhancement Imaging in Patients With Atherosclerosis.), which is not on this map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06551805 recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Research Protocol of Ferumoxytol for Magnetic Resonance Enhancement Imaging in Patients With Atherosclerosis.

TypeobservationalSponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolRan2024 to 2026Enrolled100ConditionsAtherosclerosisArmsSafety assessment of Ferumoxytol., Assessment of the diagnostic value of Ferumoxytol for MR angiography.
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
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  9. Article
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  11. Article
  12. Magnetic resonance imaging of renal oxygenation.Nature reviews. Nephrology · 2025
    Review
  13. Article
  14. Ferumoxytol-enhanced cardiovascular magnetic resonance imaging: applications and technical advances.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Review
  15. Review
  16. Review
  17. Review
  18. Review
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  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michael D Hope1 All authors: Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628.
Thomas A Hope1 All authors: Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628.
Chengcheng Zhu1 All authors: Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628.
Farshid Faraji1 All authors: Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628.
Henrik Haraldsson1 All authors: Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628.
Karen G Ordovas1 All authors: Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628.
David Saloner1 All authors: Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628.
University of California, San Francisco · US

Funding

MRI of Structure and Function in Assessing Hemodynamic Impact on AAA EvolutionR01HL114118 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI SALONER, DAVID A · 2014 to 2017
$1.8M
Hemodynamic and inflammatory imaging in evaluation of abdominal aortic aneurysmsR01HL123759 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOPE, MICHAEL DOUGLAS · 2015 to 2018
$1.6M
NHLBI NIH HHS R01 HL114118NHLBI NIH HHS R01 HL123759
6 · The paper itself

Abstract

objectiveFerumoxytol is increasingly reported as an alternative to gadolinium-based contrast agents for MR angiography (MRA), particularly for patients with renal failure. This article summarizes more than 3 years of clinical experience with ferumoxytol-enhanced MRA for a range of indications and anatomic regions.

conclusionFerumoxytol-enhanced MRA has many advantages including that it is safe for patients with renal failure and provides a lengthy plateau of vascular signal as a blood pool agent that allows longer navigated MRA sequences.

Indexed as

Contrast MediaFerrosoferric OxideMagnetic Resonance AngiographyAgedAged, 80 and overFemaleHumansImage EnhancementImaging, Three-DimensionalMaleMiddle AgedRetrospective StudiesVascular DiseasesContrast MediaFerrosoferric Oxide4D flowcontrast agentsferumoxytolinflammationMR angiography (MRA)navigated MRAultrasmall superparamagnetic iron oxide (USPIO)

Identifiers

PMID26102308
PMCPMC5130335
OpenAlexW1830656716

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.