ArticleMolecules (Basel, Switzerland)2015
Individual Constituents from Essential Oils Inhibit Biofilm Mass Production by Multi-Drug Resistant Staphylococcus aureus.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 71 citations in OpenAlex.
- Elucidating chromosomal ARGs in environmental Aeromonas spp. from hospital effluent impacted waterbodies: antagonistic potential by plant-based antimicrobials.Molecular biology reports · 2025Article
- A trans-acting sRNA SaaS targeting hilD, cheA and csgA to inhibit biofilm formation of S. Enteritidis.Journal of advanced research · 2025Article
- Investigating the Antimicrobial Properties of Essential Oil Constituents and Their Mode of Action.Molecules (Basel, Switzerland) · 2024Article
- Biomimetic Antifungal Materials: Countering the Challenge of Multidrug-Resistant Fungi.Biomimetics (Basel, Switzerland) · 2024Review
- Natural compounds in the fight againstFrontiers in pharmacology · 2024Review
- Effect of High-Pressure Micro-Fluidization on the Inactivation ofFoods (Basel, Switzerland) · 2023Article
- Antibiofilm Activities of Borneol-Citral-Loaded Pickering Emulsions against Pseudomonas aeruginosa and Staphylococcus aureus in Physiologically Relevant Chronic Infection Models.Microbiology spectrum · 2022Article
- Bacterial biofilms and their resistance mechanisms: a brief look at treatment with natural agents.Folia microbiologica · 2022Review
- Antioxidants of Fruit Extracts as Antimicrobial Agents against Pathogenic Bacteria.Antioxidants (Basel, Switzerland) · 2022Review
- Innovative next-generation therapies in combating multi-drug-resistant and multi-virulent Escherichia coli isolates: insights from in vitro, in vivo, and molecular docking studies.Applied microbiology and biotechnology · 2022Article
- Recent advances to combat ESKAPE pathogens with special reference to essential oils.Frontiers in microbiology · 2022Review
- Untargeted Metabolomics Approach of Cross-Adaptation inFrontiers in microbiology · 2022Article
- Decoding antibacterial and antibiofilm properties of cinnamon and cardamom essential oils: a combined molecular docking and experimental study.AMB Express · 2021Article
- Citral modulates virulence factors in methicillin-resistant Staphylococcus aureus.Scientific reports · 2021Article
- Exploring Phytochemicals for Combating Antibiotic Resistance in Microbial Pathogens.Frontiers in pharmacology · 2021Review
- Essential Oils Biofilm Modulation Activity, Chemical and Machine Learning Analysis. Application onInternational journal of molecular sciences · 2020Article
- Lemon Grass Essential Oil Does not Modulate Cancer Cells Multidrug Resistance by Citral-Its Dominant and Strongly Antimicrobial Compound.Foods (Basel, Switzerland) · 2020Article
- Antibacterial Effect of Thymol Loaded SBA-15 Nanorods Incorporated in PCL Electrospun Fibers.Nanomaterials (Basel, Switzerland) · 2020Article
- Biomimetic antimicrobial material strategies for combating antibiotic resistant bacteria.Biomaterials science · 2020Review
- Machine Learning Analyses on Data including Essential Oil Chemical Composition and In Vitro Experimental Antibiofilm Activities againstMolecules (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilm formation by Staphylococcus aureus represents a problem in both the medical field and the food industry, because the biofilm structure provides protection to embedded cells and it strongly attaches to surfaces. This circumstance is leading to many research programs seeking new alternatives to control biofilm formation by this pathogen. In this study we show that a potent inhibition of biofilm mass production can be achieved in community-associated methicillin-resistant S. aureus (CA-MRSA) and methicillin-sensitive strains using plant compounds, such as individual constituents (ICs) of essential oils (carvacrol, citral, and (+)-limonene). The Crystal Violet staining technique was used to evaluate biofilm mass formation during 40 h of incubation. Carvacrol is the most effective IC, abrogating biofilm formation in all strains tested, while CA-MRSA was the most sensitive phenotype to any of the ICs tested. Inhibition of planktonic cells by ICs during initial growth stages could partially explain the inhibition of biofilm formation. Overall, our results show the potential of EOs to prevent biofilm formation, especially in strains that exhibit resistance to other antimicrobials. As these compounds are food additives generally recognized as safe, their anti-biofilm properties may lead to important new applications, such as sanitizers, in the food industry or in clinical settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.