ReviewNeuroscience2016
Mouse models of fear-related disorders: Cell-type-specific manipulations in amygdala.
Review in Neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Cpeb1 remodels cell type-specific translational program to promote fear extinction.Science advances · 2025Article
- Molecular diversity and functional dynamics in the central amygdala.Frontiers in molecular neuroscience · 2024Review
- Automated Segmentation of the Mouse Body Language to Study Stimulus-Evoked Emotional Behaviors.eNeuro · 2023Article
- Human fear neurobiology reimagined: Can brain-derived biotypes predict fear-based disorders after trauma?Neuroscience and biobehavioral reviews · 2023Review
- Region-Specific Vulnerability of the Amygdala to Injury-Induced Spreading Depolarization.Biomedicines · 2022Article
- Article
- Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain.Frontiers in pharmacology · 2022Article
- Neurokinin B-Expressing Neurons of the Central Extended Amygdala Mediate Inhibitory Synaptic Input onto Melanin-Concentrating Hormone Neuron Subpopulations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Thalamic volume and fear extinction interact to predict acute posttraumatic stress severity.Journal of psychiatric research · 2021Observational
- Secretagogin marks amygdaloid PKCδ interneurons and modulates NMDA receptor availability.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Distinctive Regulation of Emotional Behaviors and Fear-Related Gene Expression Responses in Two Extended Amygdala Subnuclei With Similar Molecular Profiles.Frontiers in molecular neuroscience · 2021Article
- Multidimensional processing in the amygdala.Nature reviews. Neuroscience · 2020Review
- Article
- Rho GTPases in the Amygdala-A Switch for Fears?Cells · 2020Review
- Lacosamide intake during pregnancy increases the incidence of foetal malformations and symptoms associated with schizophrenia in the offspring of mice.Scientific reports · 2020Article
- A computationally inspired in-vivo approach identifies a link between amygdalar transcriptional heterogeneity, socialization and anxiety.Translational psychiatry · 2019Article
- Neuromodulation Strategies in Post-Traumatic Stress Disorder: From Preclinical Models to Clinical Applications.Brain sciences · 2019Review
- Common neurocircuitry mediating drug and fear relapse in preclinical models.Psychopharmacology · 2019Review
- Lost in translation: how to upgrade fear memory research.Molecular psychiatry · 2018Article
- Inhibition in the amygdala anxiety circuitry.Experimental & molecular medicine · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Fear conditioning is a model system used to study threat responses, fear memory and their dysregulation in a variety of organisms. Newly developed tools such as optogenetics, Cre recombinase and DREADD technologies have allowed researchers to manipulate anatomically or molecularly defined cell subtypes with a high degree of temporal control and determine the effect of this manipulation on behavior. These targeted molecular techniques have opened up a new appreciation for the critical contributions different subpopulations of cells make to fear behavior and potentially to treatment of fear and anxiety disorders. Here we review progress to date across a variety of techniques to understand fear-related behavior through the manipulation of different cell subtypes within the amygdala.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.