Evidence map›Paper›PMID 26101845›Full record

Observational studyArchives of physical medicine and rehabilitation2015

Pain Sensitivity and Pain Catastrophizing Are Associated With Persistent Pain and Disability After Lumbar Spine Surgery.

Rogelio A Coronado, Steven Z George, Clinton J Devin, Stephen T Wegener, Kristin R Archer

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Archives of physical medicine and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05461092 (Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion), which is not on this map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05461092 early_phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

TypeinterventionalSponsorUniversity of IowaRan2024 to 2026Enrolled50ConditionsDelirium, Pain, Back, Spinal Fusion, Thoracolumbar Interfascial Plane BlockArmsThoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring, Generalized Anxiety Disorder 7-item (GAD-7) scale, Numerical Rating Score (NRS)
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rogelio A CoronadoDepartment of Orthopaedic Surgery, Vanderbilt University, Nashville, TN.
Steven Z GeorgeDepartment of Physical Therapy, University of Florida, Gainesville, FL; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL.
Clinton J DevinDepartment of Orthopaedic Surgery, Vanderbilt University, Nashville, TN.
Stephen T WegenerDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD.
Kristin R ArcherDepartment of Orthopaedic Surgery, Vanderbilt University, Nashville, TN; Department of Physical Medicine and Rehabilitation, Vanderbilt University, Nashville, TN. Electronic address: kristin.archer@vanderbilt.edu.
Vanderbilt University · USJohns Hopkins University · USUniversity of Florida · US

Funding

Cognitive-Behavioral Based Physical Therapy: Improving Surgical Spine OutcomesR21AR062880 · NIAMS · VANDERBILT UNIVERSITY · PI ARCHER, KRISTIN · 2012 to 2013
$393k
NIAMS NIH HHS R21 AR062880
6 · The paper itself

Abstract

objectiveTo examine whether pain sensitivity and pain catastrophizing are associated with persistent pain and disability after lumbar spine surgery.

designProspective observational cohort study.

settingAcademic medical center.

participantsPatients (N=68; mean age, 57.9±13.1y; 40 women [58.8%]) undergoing spine surgery for a degenerative condition from March 1, 2012 to April 30, 2013 were assessed 6 weeks, 3 months, and 6 months after surgery.

interventionsNot applicable.

main outcome measuresThe main outcome measures were persistent back pain intensity, pain interference, and disability. Patients with persistent back pain intensity, pain interference, or disability were identified as those patients reporting Brief Pain Inventory scores ≥4 and Oswestry Disability Index scores ≥21 at all postoperative time points.

resultsFrom 6 weeks to 6 months after surgery, approximately 12.9%, 24.2%, and 46.8% of patients reported persistent back pain intensity, pain interference, or disability, respectively. Increased pain sensitivity at 6 weeks was associated with having persistent back pain intensity (odds ratio [OR], 2.0; 95% confidence interval [CI], 1.0-4.1) after surgery. Increased pain catastrophizing at 6 weeks was associated with having persistent back pain intensity (OR, 1.1; 95% CI, 1.0-1.2), pain interference (OR, 1.1; 95% CI, 1.0-1.2), and disability (OR, 1.3; 95% CI, 1.1-1.4). An interaction effect was not found between pain sensitivity and pain catastrophizing on persistent outcomes (P>.05).

conclusionsThe findings suggest the importance of early postoperative screening for pain sensitivity and pain catastrophizing to identify patients at risk for poor postoperative pain intensity, pain interference, and/or disability outcomes. Future research should consider the benefit of targeted therapeutic strategies for patients with these postoperative prognostic factors.

Indexed as

CatastrophizationAgedDisability EvaluationFemaleHumansLow Back PainMaleMiddle AgedPain MeasurementPain ThresholdPostoperative PainProspective StudiesRisk FactorsSpinal StenosisCatastrophizationLow back painLumbar stenosisPain thresholdPrognosisRehabilitation

Identifiers

PMID26101845
PMCPMC4601931
OpenAlexW1807424513

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.