Evidence map›Paper›PMID 26101533›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2015

Effects of a Dietary Supplement with Barley Sprout Extract on Blood Cholesterol Metabolism.

A Ri Byun, Hyejin Chun, Jin Lee, Sang Wha Lee, Hong Soo Lee, Kyung Won Shim

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  11. Changes in BeneficialPlants (Basel, Switzerland) · 2020
    Article
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  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A Ri ByunDepartment of Family Medicine, Ewha Woman's University Mokdong Hospital, Ewha Woman's University School of Medicine, Seoul, Republic of Korea.
Hyejin ChunHealth Promotion Center, Ewha Woman's University Mokdong Hospital, Seoul 158-710, Republic of Korea.
Jin LeeDepartment of Family Medicine, Ewha Woman's University Mokdong Hospital, Ewha Woman's University School of Medicine, Seoul, Republic of Korea.
Sang Wha LeeDepartment of Family Medicine, Ewha Woman's University Mokdong Hospital, Ewha Woman's University School of Medicine, Seoul, Republic of Korea.
Hong Soo LeeDepartment of Family Medicine, Ewha Woman's University Mokdong Hospital, Ewha Woman's University School of Medicine, Seoul, Republic of Korea.
Kyung Won ShimDepartment of Family Medicine, Ewha Woman's University Mokdong Hospital, Ewha Woman's University School of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. Barley sprout (Hordeum vulgare L.) contains 4.97% fat, 52.6% polysaccharide, and 34.1% protein along with a variety of vitamins, minerals, and polyphenolic compounds. Hexacosanol is one such compound from the barley leaf that might improve cholesterol metabolism by decreasing cholesterol synthesis. Method. Therefore, this study was conducted to investigate the effects of barley sprout extract on serum lipid metabolism in healthy volunteers (n = 51). Subjects were randomly divided into two groups: one group consumed a single capsule of barley leaf extract daily (n = 25, 42.48 ± 13.58 years) and the other consumed placebo capsules (n = 26, 40.54 ± 11.1 years) for 12 weeks. Results. After 12 weeks, total cholesterol and low-density lipoprotein- (LDL-) cholesterol were not lower in the barley sprout extract group compared to the placebo group (p = 0.415 and p = 0.351, resp.) and no differences in clinical or laboratory findings were observed between both groups. Conclusion. Our study failed to show significant lipid-lowering effects of barley sprout extract, possibly due to dosage, duration of therapy, and small sample size. Despite our nonsignificant findings, barley sprout has a possibility as a functional health food; therefore future research is needed.

Identifiers

PMID26101533
PMCPMC4458530

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.