ArticlePakistan journal of medical sciences
Scrub typhus associated hepatic dysfunction and abdominal CT findings.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- Imaging in scrub typhus - a pictorial review.Abdominal radiology (New York) · 2026Review
- Concurrent splenic and renal infarction in scrub typhus: expanding the vasculitic spectrum.BMC infectious diseases · 2026Article
- Unveiling the unseen: generalized myoclonus status and MODS in scrub typhus, a case report and literature review.BMC infectious diseases · 2025Review
- Pneumonia due to scrub typhus infection: a case report.BMC pulmonary medicine · 2025Article
- Spontaneous splenic rupture associated with scrub typhus: a case report.Infectious diseases of poverty · 2024Article
- Clinical profile and biochemical abnormalities in Scrub Typhus: A cross-sectional study.Annals of medicine and surgery (2012) · 2022Article
- A time-course comparative clinical and immune response evaluation study between the human pathogenic Orientia tsutsugamushi strains: Karp and Gilliam in a rhesus macaque (Macaca mulatta) model.PLoS neglected tropical diseases · 2022Article
- Article
- A Case of Scrub Typhus complicated with a Splenic Infarction.Infection & chemotherapy · 2018Article
- Scrub typhus: radiological and clinical findings in abdominopelvic involvement.Japanese journal of radiology · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis retrospective study investigated abnormal hepatic dysfunction and abdominal computed tomography (CT) findings in scrub typhus.
methodsThree hundred forty nine adult patients were diagnosed with scrub typhus. Ninety four underwent abdominal CT. The CT images were reviewed by the attending radiologist. Patient data of history, symptoms, signs, and results of laboratory tests were collected from the electronic medical records.
resultsIn 349 patients with scrub typhus, elevation of aspartate aminotransferase (78.5%) and alanine aminotransferase (63.0%) were dominant compared to alkaline phosphatase (27.2%) and total bilirubin (16.1%). Abdominal CT findings of 94 patients were, in descending order of frequency, enlarged lymph node (53.2%), inhomogeneous enhancement of liver (47.9%), splenomegaly (46.8%), ascites (28.7%), low attenuation of periportal areas (27.7%), gallbladder wall thickening (17.0%), and splenic infarct (6.4%). Also, the level of aspartate aminotransferase tended to be elevated according to the number of CT findings (P= 0.028).
conclusionsWe found that abdominal CT manifestations of scrub typhus with elevated aminotransferases were varied and not specific. However, knowledge of these findings may evoke the recognition of scrub typhus by clinicians in endemic areas.
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