ArticleClinical and molecular allergy : CMA2015
Choosing wisely: practical considerations on treatment efficacy and safety of asthma in the elderly.
Article in Clinical and molecular allergy : CMA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Early Initiation of Biologic Therapies to Prevent Severe Asthma Progression.Medicina (Kaunas, Lithuania) · 2025Review
- Rhinitis in the Geriatric Population: Epidemiological and Cytological Aspects.Geriatrics (Basel, Switzerland) · 2025Review
- Article
- Asthma Care in the Elderly: Practical Guidance and Challenges for Clinical Management - A Framework of 5 "Ps".Journal of asthma and allergy · 2023Review
- Health-care Resource Requirements and Potential Financial Consequences of an Environmentally Driven Switch in Respiratory Inhaler Use in England.Journal of health economics and outcomes research · 2021Article
- Clinical profile of chronic bronchial asthma patients in Poland: results of the PROKSAL study.Postepy dermatologii i alergologii · 2020Article
- GPs should not try to detect mild COPD.NPJ primary care respiratory medicine · 2020Article
- Efficacy and Safety of Sublingual Immunotherapy in Elderly Rhinitis Patients Sensitized to House Dust Mites.Allergy, asthma & immunology research · 2018Article
- Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms.Clinical and molecular allergy : CMA · 2017Review
- How to fit allergen immunotherapy in the elderly.Clinical and molecular allergy : CMA · 2017Review
- Asthma in the elderly: a different disease?Breathe (Sheffield, England) · 2016Review
- Appropriateness in allergic respiratory diseases health care in Italy: definitions and organizational aspects.Clinical and molecular allergy : CMA · 2016Article
- Pharmacotherapy in the management of asthma in the elderly: a review of clinical studies.Asia Pacific allergy · 2016Review
- Asthma phenotypes: the intriguing selective intervention with Montelukast.Asthma research and practice · 2016Review
- Use of ICS/LABA (extra-fine and non-extra-fine) in elderly asthmatics.Therapeutics and clinical risk management · 2016Review
- Choosing wisely in Allergology: a Slow Medicine approach to the discipline promoted by the Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC).Clinical and molecular allergy : CMA · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 17 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of asthma in the most advanced ages is similar to that of younger ages. However, the concept that older individuals may suffer from allergic asthma has been largely denied in the past, and a common belief attributes to asthma the definition of "rare" disease. Indeed, asthma in the elderly is often underdiagnosed or diagnosed as COPD, thus leading to undertreatment of improper treatment. This is also due to the heterogeneity of clinical and functional presentations of geriatric asthma, including the partial loss of reversibility and the lower occurrence of the allergic component in this age range. The older asthmatic patients are also characterized the coexistence of comorbid conditions that, in conjunction with age-associated structural and functional changes of the lung, may contribute to complicate the management of asthma. The current review addresses the main issues related to the management of allergic asthma in the geriatric age. In particular, the paper aims at revising current pharmacological and non pharmacological treatments for allergic asthmatics of advanced ages, primarily focusing on their safety and efficacy, although most behaviors are an arbitrary extrapolation of what has been tested in young ages. In fact, age has always represented an exclusion criterion for eligibility to clinical trials. Experimental studies and real life observations specifically testing the efficacy and safety of therapeutic approaches in allergic asthma in the elderly are urgently needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.