Evidence map›Paper›PMID 26101300›Full record

ArticleBMJ case reports2015

Squamous cell carcinoma of unknown origin metastasising to the right atrium causing acute heart failure.

David Sladden, Kentaro Yamagata, Elton Pllaha, Walter Busuttil

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

David SladdenDepartment of Cardiothoracic Surgery, Mater Dei Hospital, Msida, Malta.
Kentaro YamagataDepartment of Cardiology, Mater Dei Hospital, Msida, Malta.
Elton PllahaDepartment of Cardiology, Mater Dei Hospital, Msida, Malta.
Walter BusuttilDepartment of Cardiothoracic Surgery, Mater Dei Hospital, Msida, Malta.
Mater Dei Hospital · MT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of metastasis to the heart, which was initially suspected to be a myxoma, causing acute right heart failure. Emergency surgery was carried out by opening the right atrium and superior vena cava, and debulking the tumour in a piecemeal fashion, providing temporary relief of symptoms. The histology showed this to be metastatic squamous cell carcinoma possibly of head and neck origin. This is extremely rare, with few published cases. Full endoscopic and CT, including positron emission tomography CT, investigation of the head and neck was performed with no primary findings. Only two such cases of squamous cell carcinoma of unknown origin metastasising to the heart have been described, and, in both cases, the patients died within several weeks of diagnosis. This patient remains alive 2 months postoperatively and is receiving radiotherapy to the chest, but his prognosis remains poor.

Indexed as

AgedCarcinoma, Squamous CellDiagnosis, DifferentialHeart AtriaHeart FailureHeart NeoplasmsHumansMaleMyxomaTreatment Outcome

Identifiers

PMID26101300
PMCPMC4480105
OpenAlexW2265233934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.