Observational studyClinical cardiology2015
Burden of First and Recurrent Cardiovascular Events Among Patients With Hyperlipidemia.
Observational study in Clinical cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A Systematic Review and Meta-Analysis of Ayurvedic Herbal Preparations for Hypercholesterolemia.Medicina (Kaunas, Lithuania) · 2021Pooled it
- A Systematic Review of Medical Costs Associated with Heart Failure in the USA (2014-2020).PharmacoEconomics · 2020Pooled it
- A Systematic Review of Direct Cardiovascular Event Costs: An International Perspective.PharmacoEconomics · 2019Pooled it
- Cost-effectiveness of inclisiran in patients with atherosclerotic cardiovascular disease from Chinese healthcare perspective.PloS one · 2026Article
- Acute stroke care coordination in the United States: Variation in state laws for Emergency Medical Services and hospitals.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025Article
- Implications of Payment for Acute Myocardial Infarctions as a 90-Day Bundled Single Episode of Care: A Cost of Illness Analysis.PharmacoEconomics - open · 2022Article
- Cardiovascular event rate and death in high-risk secondary prevention patient cohort in Finland: A registry study.Clinical cardiology · 2022Article
- Cost-Effectiveness Analysis of Evolocumab for the Treatment of Dyslipidemia in the Kingdom of Saudi Arabia.PharmacoEconomics - open · 2022Article
- Prevalence and Risk Factors of Dyslipidemia among Type 2 Diabetes Patients at a Referral Hospital, North Eastern Ethiopia.Ethiopian journal of health sciences · 2021Article
- Lipid treatment and goal attainment characteristics among persons with atherosclerotic cardiovascular disease in the United States.American journal of preventive cardiology · 2020Article
- Incidence and risk factors for recurrent cardiovascular disease in middle-eastern adults: a retrospective study.BMC cardiovascular disorders · 2019Article
- Lipid-Lowering Prescription Patterns in Patients With Diabetes Mellitus or Cardiovascular Disease.The American journal of cardiology · 2019Article
- Activation of 5-HTScientific reports · 2019Article
- Cardiovascular event rates in a high atherosclerotic cardiovascular disease risk population: estimates from Swedish population-based register data.European heart journal. Quality of care & clinical outcomes · 2019Article
- PCSK9 Inhibitor Use in the Real World: Data From the National Patient-Centered Research Network.Journal of the American Heart Association · 2019 · on this mapArticle
- Hospital and Institutionalisation Care Costs after Limb and Visceral Ischaemia Benchmarked Against Stroke: Long-Term Results of a Population Based Cohort Study.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2018Article
- Cost-effectiveness of Evolocumab Therapy for Reducing Cardiovascular Events in Patients With Atherosclerotic Cardiovascular Disease.JAMA cardiology · 2017 · on this mapArticle
- A Retrospective Study to Examine Healthcare Costs Related to Cardiovascular Events in Individuals with Hyperlipidemia.Advances in therapy · 2015Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute cardiovascular (CV) events have been evaluated in patients with specific comorbidities but have not focused on patients with hyperlipidemia or on the their long-term costs.
objectivesTo evaluate incidence of CV events, costs, and resource utilization among patients with hyperlipidemia and baseline risk of CV disease (CVD).
methodsPatients (age 18 to 64 years) diagnosed with hyperlipidemia or using lipid-modifying medications were identified from administrative claims. Patients were categorized into 3 cohorts based on pre-index clinical characteristics-secondary prevention (SP; history of CV event, n = 15 613); high risk (HR; CVD, n = 47 600); and primary prevention (PP; no CV event history or CVD, n = 60 637)-and followed up to 2 years after the CV event.
resultsDuring follow-up, ≥1 new CV event occurred in 43.0% of the SP cohort, 33.9% of HR, and 20.9% of PP; and ≥3 new events occurred in 19.8% of the SP cohort, 12.9% of HR, and 5.5% of PP. Incremental total costs were $19 320 for SP, $20 003 for HR, and $17 650 for PP. Compared with patients with only 1 CV event, the mean 2-year cost was 30% higher in patients with 2 CV events and 48% higher in patients with 3 CV events. Only 50% of HR patients (with or without CV events) received statins.
conclusionsPatients with recurrent CV events had higher total health care costs during 24-month follow-up for each type of CV event. Total health care costs among patients with a CV event were higher for the initial as well as subsequent events. Statins and lipid-modifying medications were significantly underutilized in all cohorts, despite the presence of CVD.
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