Evidence map›Paper›PMID 26100719›Full record

Trial reportJournal of advanced nursing2015

A randomized controlled trial of the feasibility and preliminary efficacy of a texting intervention on medication adherence in adults prescribed oral anti-cancer agents: study protocol.

Sandra L Spoelstra, Charles W Given, Alla Sikorskii, Constantinos K Coursaris, Atreyee Majumder, Tracy DeKoekkoek, Monica Schueller, Barbara A Given

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of advanced nursing, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Would the Siblings of Latinx Men Who Have Sex With Men Encourage Their Brothers to Use PrEP? Findings From a Feasibility and Acceptability Study.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
    Article
  4. Article
  5. Technology use and its association with health and depressive symptoms in older cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  6. The Evolution of Gero-Oncology Nursing.Seminars in oncology nursing · 2016
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sandra L SpoelstraCollege of Nursing, Michigan State University, East Lansing, Michigan, USA.
Charles W GivenInstitute for Health Care Studies, Michigan State University, East Lansing, Michigan, USA.
Alla SikorskiiDepartment of Statistics and Probability, Michigan State University, East Lansing, Michigan, USA.
Constantinos K CoursarisDepartment of Telecommunication, Information Studies (Dr. Coursaris), Michigan State University, East Lansing, Michigan, USA.
Atreyee MajumderDepartment of Statistics and Probability, Michigan State University, East Lansing, Michigan, USA.
Tracy DeKoekkoekCollege of Nursing, Michigan State University, East Lansing, Michigan, USA.
Monica SchuellerCollege of Nursing, Michigan State University, East Lansing, Michigan, USA.
Barbara A GivenCollege of Nursing, Michigan State University, East Lansing, Michigan, USA.
Michigan State University · US

Funding

Text Messaging to Improve Adherence to Oral Chemotherapy AgentsR15CA176595 · NCI · MICHIGAN STATE UNIVERSITY · PI SPOELSTRA, SANDRA LEE · 2013 to 2013
$465k
NCI NIH HHS 1R15CA176595NCI NIH HHS R15 CA176595
6 · The paper itself

Abstract

aimThe aim of this study was to report a study protocol that examines feasibility, preliminary efficacy and satisfaction of a text message intervention on the outcome of medication adherence in adult patients prescribed oral anti-cancer agents.

backgroundAdministration of oral anti-cancer agents occurs in the home setting, requiring patients to self-manage the regimen as prescribed. However, many barriers to medication adherence exist: regimens are often complex, with cycling of two or more medications; side effects of treatment; most cancer patients are older with comorbid conditions and competing demands; and cognitive decline and forgetfulness may occur. Research indicates patients miss nearly one-third of the prescribed oral anti-cancer agent dosages. Text message interventions have been shown to improve medication adherence in chronic conditions other than cancer. However, a majority of those patients were less than 50 years of age and most cancer patients are diagnosed later in life.

designA two-group randomized controlled trial with repeated measures.

methodsSeventy-five adult patients newly prescribed an oral anti-cancer agent will be recruited (project funded in April 2013) from community cancer centres and a specialty pharmacy. Participants will be randomized to either a control group (n = 25; usual care) or an intervention group (n = 50; usual care plus text messages timed to medication regimen). Outcome measures include: medication adherence, feasibility and satisfaction with the intervention. Data will be collected over 8 weeks: baseline, weekly and exit. DISCUSSION: Standardized text message intervention protocol and detailed study procedures have been developed in this study to improve medication adherence.

Indexed as

Medication AdherencePatient SatisfactionText MessagingAdministration, OralAdultAgedAged, 80 and overAntineoplastic AgentsCell PhoneFemaleHumansMaleMiddle AgedNeoplasmsSelf CareAntineoplastic Agentscancerinterventionmedication adherencemHealthnursingoral anti-cancer agentrandomized controlled trialrecruitmenttext messaging

Identifiers

PMID26100719
PMCPMC4689681
OpenAlexW1830460460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.