Melanoma: CheckMate 067--frontline nivolumab improves PFS alone or in combination with ipilimumab.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

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2. Mutations in the RAS/MAPK Pathway Drive Replication Repair-Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition.Cancer discovery · 2021
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3. Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma.Oncoimmunology · 2021
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4. T cell immunoglobulin and mucin-domain containing-3 in non-small cell lung cancer.Translational lung cancer research · 2019
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5. STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy.Biomaterials · 2018
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6. Immunotherapy: A New (and Old) Approach to Treatment of Soft Tissue and Bone Sarcomas.The oncologist · 2018
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7. PD-1, PD-L1 Protein Expression in Non-Small Cell Lung Cancer and Their Relationship with Tumor-Infiltrating Lymphocytes.Medical science monitor : international medical journal of experimental and clinical research · 2017
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8. PD-1 blockade restores impaired function of ex vivo expanded CD8OncoTargets and therapy · 2017
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9. Major histocompatibility complex class I expression impacts on patient survival and type and density of immune cells in biliary tract cancer.British journal of cancer · 2015
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10. A Perspective of Immunotherapy for Breast Cancer: Lessons Learned and Forward Directions for All Cancers.Breast cancer : basic and clinical research · 2015
    Review
11. The Treatment for a Patient with Cancer of Unknown Primary: A Case Report.Dose-response : a publication of International Hormesis Society
    Article

Corrections and comments

• Comment on
  Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma.2015

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as