ArticleBMC plant biology2015
Arabidopsis leucine-rich repeat extensin (LRX) proteins modify cell wall composition and influence plant growth.
Article in BMC plant biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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Who cites it
58 citing papers in PubMed, 121 citations in OpenAlex.
- Leucine-Rich Repeat Extension 7 Gene Confers Cotton Resistance to Verticillium Wilt.International journal of molecular sciences · 2026Article
- The Arabidopsis phosphatase PP2C12 negatively regulates LRX-RALF-FER-mediated cell wall integrity sensing.The EMBO journal · 2026Article
- Identification of candidate genes and proteins for tasseling stage drought tolerance through integrated transcriptomic and proteomic analysis approach in maize.BMC plant biology · 2025Article
- Advanced imaging-enabled understanding of cell wall remodeling mechanisms mediating plant drought stress tolerance.Frontiers in plant science · 2025Review
- Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases.Computational and structural biotechnology journal · 2024Article
- Genome-wide identification and characterization of the LRX gene family in grapevine (Vitis vinifera L.) and functional characterization of VvLRX7 in plant salt response.BMC genomics · 2024Article
- Whole-Genome Sequencing and Analysis of Tumour-Forming Radish (International journal of molecular sciences · 2024Article
- Phase separation: a new window in RALF signaling.Frontiers in plant science · 2024Article
- Growth-inhibiting effects of the unconventional plant APYRASE 7 of Arabidopsis thaliana influences the LRX/RALF/FER growth regulatory module.PLoS genetics · 2024Article
- Emerging Roles of Receptor-like Protein Kinases in Plant Response to Abiotic Stresses.International journal of molecular sciences · 2023Review
- RALF peptides modulate immune response in the mossFrontiers in plant science · 2023Article
- The zinc finger protein 3 ofFrontiers in plant science · 2023Article
- A novel mitochondrial protein is required for cell wall integrity, auxin accumulation and root elongation in Arabidopsis under salt stress.Stress biology · 2022Article
- Remodeling of Cell Wall Components in Root Nodules and Flower Abscission Zone under Drought in Yellow Lupine.International journal of molecular sciences · 2022Article
- Investigation of cell wall proteins of C. sinensis leaves by combining cell wall proteomics and N-glycoproteomics.BMC plant biology · 2021Article
- Maintenance of Cell Wall Integrity under High Salinity.International journal of molecular sciences · 2021Review
- Utilization of a Wheat55K SNP array-derived high-density genetic map for high-resolution mapping of quantitative trait loci for important kernel-related traits in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Multi-scale comparative transcriptome analysis reveals key genes and metabolic reprogramming processes associated with oil palm fruit abscission.BMC plant biology · 2021Article
- Physiological and Biochemical Traits of Two MajorFrontiers in plant science · 2021Article
- Novel and Transgressive Salinity Tolerance in Recombinant Inbred Lines of Rice Created by Physiological Coupling-Uncoupling and Network Rewiring Effects.Frontiers in plant science · 2021Article
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Authors and funding
11 authors at 7 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeucine-rich repeat extensins (LRXs) are extracellular proteins consisting of an N-terminal leucine-rich repeat (LRR) domain and a C-terminal extensin domain containing the typical features of this class of structural hydroxyproline-rich glycoproteins (HRGPs). The LRR domain is likely to bind an interaction partner, whereas the extensin domain has an anchoring function to insolubilize the protein in the cell wall. Based on the analysis of the root hair-expressed LRX1 and LRX2 of Arabidopsis thaliana, LRX proteins are important for cell wall development. The importance of LRX proteins in non-root hair cells and on the structural changes induced by mutations in LRX genes remains elusive.
resultsThe LRX gene family of Arabidopsis consists of eleven members, of which LRX3, LRX4, and LRX5 are expressed in aerial organs, such as leaves and stem. The importance of these LRX genes for plant development and particularly cell wall formation was investigated. Synergistic effects of mutations with gradually more severe growth retardation phenotypes in double and triple mutants suggest a similar function of the three genes. Analysis of cell wall composition revealed a number of changes to cell wall polysaccharides in the mutants.
conclusionsLRX3, LRX4, and LRX5, and most likely LRX proteins in general, are important for cell wall development. Due to the complexity of changes in cell wall structures in the lrx mutants, the exact function of LRX proteins remains to be determined. The increasingly strong growth-defect phenotypes in double and triple mutants suggests that the LRX proteins have similar functions and that they are important for proper plant development.
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