Evidence map›Paper›PMID 26099347›Full record

ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2015

Safety and feasibility of an enhanced recovery pathway after a liver resection: prospective cohort study.

Bobby V M Dasari, Rasha Rahman, Shakeeb Khan, Davinia Bennett, James Hodson, John Isaac, Ravi Marudanayagam, Darius F Mirza, Paolo Muiesan, Keith J Roberts and 1 more

Abstract readComparative Study
In one paragraph

Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Enhanced Recovery After Surgery (ERAS) Reduces Hospital Costs and Improve Clinical Outcomes in Liver Surgery: a Systematic Review and Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Pooled it
  2. Pooled it
  3. Enhanced Recovery after Surgery Programs for Liver Resection: a Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Pooled it
  4. Trial
  5. Review
  6. Review
  7. THERE ARE NO ADVANTAGES BETWEEN LAPAROSCOPIC AND OPEN LIVER RESECTIONS WITHIN AN ENHANCED RECOVERY PROGRAM (ERAS).Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021
    Article
  8. Article
  9. ERAS in minimally invasive hepatectomy.Annals of hepato-biliary-pancreatic surgery · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bobby V M DasariThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Rasha RahmanThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Shakeeb KhanThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Davinia BennettDepartment of Anaesthesia, Queen Elizabeth Hospital, Birmingham, UK.
James HodsonWolfson Laboratory, Queen Elizabeth Hospital, Birmingham, UK.
John IsaacThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Ravi MarudanayagamThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Darius F MirzaThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Paolo MuiesanThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Keith J RobertsThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Robert P SutcliffeThe Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn contrast to colorectal surgery, enhanced recovery pathways (ERPs) have not yet become standard practice after major upper abdominal surgery. The aim of this study was to assess the feasibility and outcomes after implementation of an ERP after liver a resection.

methodsPatients who underwent a liver resection in two consecutive 6-month periods before (July-December 2013) and after (January-June 2014) implementation of an ERP were included in a prospective study. Patients who underwent live donation, ALPPS (associating liver partition with portal vein ligation for staged hepatectomy) or concomitant procedures were excluded. Peri-operative outcomes were compared between groups, and multivariate analysis of factors influencing the length of hospital stay (LOS) was performed.

resultsTwo hundred and eleven patients (93 pre-ERP and 91 post-ERP patients) underwent a liver resection during the study period. There was no significant difference in the median LOS (P = 0.907) and 30-day readmission rates (P = 0.645) between the groups. Severe (Clavien grade III-V) complications were reduced in ERP patients (13.9% versus 4.3%; P = 0.039). On multivariate analysis, an increased age (< 0.001), open resection (< 0.001) and complications (< 0.001) were associated with an increased LOS.

conclusionEnhanced recovery after a liver resection appears to be safe, feasible and may reduce severe complications. However, the LOS was significantly influenced by patient age, open surgery and post-operative complications, but not by an ERP.

Indexed as

Critical PathwaysHepatectomyPatient SafetyAgedBody Mass IndexFeasibility StudiesFemaleHumansLength of StayLiver NeoplasmsMaleMiddle AgedNeoplasm GradingPatient ReadmissionPerioperative CarePostoperative Care

Identifiers

PMID26099347
PMCPMC4527855

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.